{"title":"Collection Favorites Products","description":"","products":[{"product_id":"creatine-monohydrate","title":"Creatine Monohydrate","description":"\u003cp\u003e- Increases lean muscle mass in resistance training\u003cbr\u003e\nCreatine is one of the most researched natural health products. It is also one of the safest and most effective supplements to support athletic performance and muscle growth. In addition to boosting athletic performance in men and women, creatine provides other benefits including healthy aging, cognitive function and bone strength, while filling nutritional gaps in plant-based diets. It also promotes the maintenance of lean body mass at all ages and healthy aging.\u003c\/p\u003e","brand":"Designs For Health","offers":[{"title":"450 g","offer_id":41005574226005,"sku":"creatine-designs-for-health-450g","price":58.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/creatine-designs-for-health-450g.png?v=1739822244"},{"product_id":"magnesium-threonate","title":"Magnesium Threonate","description":"\u003cp\u003e- Each capsule contains 667 mg of Magnesium L-Threonate to better deliver magnesium to the brain, support overall cognition and improve memory.\u003cbr\u003e\n- Each capsule provides 667 mg of magnesium L-threonate complex, including 50 mg of elemental magnesium.\u003cbr\u003e\n- Threonate is a metabolite of vitamin C used to deliver magnesium across the blood-brain barrier and into the central nervous system, ultimately increasing the expression of the NDMA receptor in the hippocampus.\u003cbr\u003e\n- Magnesium threonate has been studied clinically to improve spatial memory, spatial orientation, and working memory.\u003cbr\u003e\nThe human brain is truly remarkable in its ability to regulate our many cognitive functions. Our central nervous system is responsible for complex tasks such as attention, memory, problem solving, reasoning and planning. Unfortunately, many cognitive functions tend to decline with age, and many factors can accelerate this process. This is why a good diet is essential for maintaining optimal cognition and magnesium is a key nutrient that has been identified for its role in cognition.\u003cbr\u003e\nMagnesium is necessary for the proper functioning of nerves and muscles through the regulation of calcium, the creation of cellular energy in mitochondria and its role as a cofactor in the construction of DNA, RNA and many proteins. Despite its great importance, magnesium is commonly deficient in the Canadian population due to poor diet, medication exhaustion and stress. Suboptimal levels of magnesium can also create a pro-inflammatory state in the body. All of these physiological functions governed by magnesium can affect cognition, so it is important to ensure adequate magnesium status in the central nervous system.\u003cbr\u003e\nMagnesium threonate has emerged as one of the best forms of magnesium to support brain health. Threonate is a metabolite of vitamin C that facilitates the transport of magnesium across the blood-brain barrier and into the central nervous system. An animal study showed that magnesium threonate improved spatial memory and spatial orientation after 24 days, compared to untreated subjects. Additionally, a human clinical trial showed that 1.5 to 2 grams per day of magnesium l-threonate, combined with 200 IU of vitamin D and 30 mg of vitamin C, improved working memory in subjects aged 50 to 70 years after 6 and 12 weeks, compared to a control group. Mechanistically, these results can be explained by the fact that magnesium can increase the expression of NMDA receptors in the hippocampus.\u003cbr\u003e\nCyto-Matrix Magnesium Threonate offers 667 mg of pure magnesium L-threonate complex per capsule, including 50 mg of elemental magnesium. This complex is designed to best deliver magnesium to the central nervous system, support overall cognition and improve memory. Each bottle contains 120 vegetable capsules.\u003c\/p\u003e","brand":"Cyto-Matrix","offers":[{"title":"120 capsules","offer_id":41005585465429,"sku":"magnesium-threonate-cyto-matrix-120-capsules","price":34.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/MagnesiumThreonate_Cyto-Matrix_EnergiePLP_Unytii_Supplements.png?v=1739822221"},{"product_id":"resveratrol","title":"Resveratrol","description":"\u003cp\u003e- Antioxidant\u003cbr\u003e\n- Provides 250 mg of all-natural trans-resveratrol per serving\u003cbr\u003e\n- Trans-resveratrol promotes cellular health and longevity thanks to its powerful antioxidant effects.\u003cbr\u003e\n- Activates Nrf2 and SIRT1, associated with cellular protection and healthy aging.\u003cbr\u003e\n- Resveratrol is extracted from red grapes grown in the Okanagan Valley of British Columbia and Japanese knotweed.\u003cbr\u003e\n- Suitable for vegans and vegetarians\u003cbr\u003e\nResveratrol is a natural polyphenol found in many plants, particularly grapes and peanuts. It is widely recognized as a powerful antioxidant with multiple actions that promote longevity and cell health. Resveratrol protects against oxidative stress both through direct antioxidant effects and through the activation of cellular pathways associated with antioxidant defense. This includes stimulation of the potent transcription factor nuclear erythroid-related factor 2 (Nrf2), which increases the expression of multiple antioxidant enzymes associated with cardioprotective, neuroprotective, and healthy aging effects.\u003cbr\u003e\nResveratrol also activates sirtuin SIRT1, a protein responsible for regulating many essential cellular functions, including DNA repair, mitochondrial biogenesis, autophagy, inflammation, metabolism, and more. SIRT1 has been associated with life expectancy, longevity, cardiovascular function, and reduced risk of many age-related conditions. Indeed, SIRT1 is considered a “longevity gene,” as many of the benefits of calorie restriction observed in experimental studies are thought to be mediated by SIRT1 activation. Clinical trials of resveratrol have demonstrated several aging-related benefits, including increasing SIRT1 levels, improving cognitive function, and improving cardiovascular risk factors.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 capsules","offer_id":41005585891413,"sku":"resveratrol-bioclinic-60c","price":44.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/resveratrol-bioclinic-60c.png?v=1739822219"},{"product_id":"extrait-de-safran","title":"Extrait de safran","description":"\u003cp\u003e- Promotes mood and relaxation\u003cbr\u003e\n- Provides 28 mg of Affron® standardized saffron extract per capsule\u003cbr\u003e\n- Affron is clinically validated by multiple trials\u003cbr\u003e\n- Contains standardized quantities of the bioactive components of saffron, crocin and safranal.\u003cbr\u003e\n- Provides 100% pure saffron from Crocus sativus L. from Spain\u003cbr\u003e\n- Contributes to mood balance and the reduction of symptoms of perceived stress, such as fatigue, weariness and irritability.\u003cbr\u003e\n- Helps improve restful sleep and sleep quality in people suffering from insomnia.\u003cbr\u003e\n- Contributes to mood balance in adolescents and young people aged 12 and over\u003cbr\u003e\n- Non-GMO, non-irradiated and suitable for vegetarians\/vegans.\u003cbr\u003e\nSaffron is a spice derived from the Crocus sativus flower. It is rich in bioactive compounds and has been clinically shown to improve symptoms related to stress, anxiety and low mood, and to promote sleep. The active components of saffron include carotenoids, phenols and flavonoids. Its clinical effects are mainly attributed to crocin and safranal, which are also responsible for its aroma and color. Multiple controlled trials have shown that saffron improves symptoms related to nervousness, stress, and mood.\u003cbr\u003e\nMultiple mechanisms of action have been identified for saffron, including antioxidant and anti-inflammatory effects, modulation of the HPA axis, agonism of the GABAA receptor, and inhibition of reuptake of several neurotransmitters, including dopamine. Affron, a new standardized saffron extract, has been shown to decrease negative mood and symptoms related to stress and anxiety (including perceived stress and nervousness, tension, sadness, and fatigue) in several randomized, controlled trials in adults, with similar benefits in a controlled trial in adolescents aged 12 to 16 years. Affron also improved clinician-rated mood scores when combined with standard therapies. Additionally, affron has been shown to improve sleep quality in participants with self-reported sleep problems and increase evening melatonin levels.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"30 capsules","offer_id":41005588774997,"sku":"safran-bioclinic-30c","price":34.99,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/safran-bioclinic-30c.png?v=1739822215"},{"product_id":"opti-ova-female-wellness-kit","title":"Opti Ova Female Wellness Kit","description":"\u003cp\u003e- Provides comprehensive nutritional support, with therapeutic dosages, for various factors affecting reproductive health.\u003cbr\u003e\n- Broad-spectrum antioxidants reduce oxidative stress and damage, and improve mitochondrial function, key determinants of oocyte function and quality.\u003cbr\u003e\n- Provides the most bioavailable forms of nutrients including pyridoxal 5'-phosphate, d-alpha tocopheryl, vitamin D3, methylcobalamin, and (6S)-5-methyltetrahydrofolic acid.\u003cbr\u003e\n- Promotes good blood circulation in the endometrium, providing nutrients, removing toxins and reactive oxygen species (ROS) from the endometrium, and encouraging proper implantation.\u003cbr\u003e\nOpti Ova is a comprehensive female reproductive support kit that provides an effective combination of key antioxidants, omega-3 fatty acids, vitamins and minerals that have been shown to improve egg quality and boost fertility. By optimizing mitochondrial function, reducing oxidative stress, promoting blood flow to the endometrium and its development, and improving detoxification pathways, Opti Ova provides a broad base of nutritional support for reproductive health.\u003cbr\u003e\nMitochondrial activity is a key factor in oocyte function and quality, with mitochondrial dysfunction recognized as a major cause of age-induced decline in oocyte quality. Key nutrients including PQQ, resveratrol, and CoQ10 have been shown to induce mitochondrial biogenesis, counteract ovarian aging, and, when combined with clomiphene citrate, CoQ10 supplementation increased clinical pregnancy rates by more than 6-fold compared to clomiphene alone, in a prospective randomized trial of participants with PCOS.\u003cbr\u003e\nN-acetylcysteine ​​provides the limiting factor for the production of glutathione, essential for the detoxification of many pollutants that interfere with reproductive function; It has also been shown to improve pregnancy rates and endometrial thickness compared to standard PCOS treatments, such as clomiphene and metformin. L-carnitine, Japanese knotweed, and magnesium are also beneficial for women with PCOS.\u003cbr\u003e\nOpti Ova contains vitamins D and E, omega-3 fatty acids, key minerals and bioavailable B vitamins that act as powerful antioxidants and support optimal endometrial health and implantation. Vitamin E supplementation alone has been shown to shorten time to pregnancy in women over 35 seeking treatment for unexplained infertility, while vitamin D has been linked to implantation rates and IVF outcomes, with higher levels linked to higher pregnancy rates.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"1 Kit","offer_id":41005597425749,"sku":"80093441","price":164.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/gmhs7chzrl9attbuplgi.jpg?v=1739822210"},{"product_id":"pcos-care","title":"PCOS Care","description":"\u003cp\u003e- Regulates the menstrual cycle, reduces testosterone\u003cbr\u003e\n- Supports fertility and healthy blood sugar levels\u003cbr\u003e\n- Provides the recommended 40:1 ratio of myo inositol to D-chiro inositol.\u003cbr\u003e\n- Contains natural forms of inositol, whose complementary effects on metabolism and ovarian function have been clinically demonstrated in women with PCOS.\u003cbr\u003e\n- Contains methylcobalamin and activated folate (L-5-MTHF) for optimal fertility and pregnancy.\u003cbr\u003e\n- Unflavored powder makes it easy to take twice a day.\u003cbr\u003e\nPCOS CARE® provides the two most common forms of inositol, natural and complementary, which have been clinically shown to improve ovarian and metabolic function in women with polycystic ovarian syndrome (PCOS). Numerous clinical trials of myo-inositol have shown a positive effect on spontaneous ovulation and meiotic maturation and quality of human oocytes, as well as improvements in metabolic risk factors and reductions in androgen levels in women with PCOS. A recent meta-analysis of seven trials showed that myo-inositol increased pregnancy rates in subfertile women undergoing ovulation induction for ICSI or IVF-ET, and reduced the number of unsuitable oocytes and medications required for ovulation.\u003cbr\u003e\nLikewise, D-chiro-inositol has been shown to improve ovarian function and metabolism, including cycle regularity, blood pressure, HOMA index, and hormones such as insulin and LH. In PCOS Care, these complementary nutrients are combined in a 40:1 ratio that has been shown to be more effective than myo-inositol alone in improving metabolic symptoms and IVF outcomes in women with PCOS, and according to the dosage ratio recommended by the International Consensus Conference on Myo-inositol and D-chiro-inositol.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"129 g","offer_id":41005597491285,"sku":"pcos-bioclinic-naturals-129g","price":35.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/rvk0tffenklqtrxr3f6q.jpg?v=1739822209"},{"product_id":"menovantage-pe™","title":"MenoVantage PE™","description":"\u003cp\u003e- Provides traditional herbs in clinical doses for relief of menopausal symptoms: Angelica sinensis (dong quai), Actaea racemosa (black cohosh), and Vitex agnus-castus (chasteberry).\u003cbr\u003e\n- Contains standardized plant extracts for consistent effects.\u003cbr\u003e\n- Contains gamma-oryzanol and hesperidin, a bioflavonoid, to relieve symptoms and provide metabolic and cardiovascular support.\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nFor many women, the transition from pre-menopause to post-menopause can be difficult. The change in hormone levels can lead to an increased risk of heart disease and osteoporosis, while also causing uncomfortable short-term problems such as vasomotor symptoms (hot flashes, night sweats), insomnia, vaginal dryness, mood changes, and reduced libido.\u003cbr\u003e\nMenoVantage PE is a powerful formulation of herbs and nutrients in clinically relevant doses to reduce perimenopausal symptoms. Black cohosh (Actaea racemosa) is one of the most studied botanical extracts for the relief of menopausal symptoms. Randomized, double-blind trials have shown a reduction in climacteric symptoms without an estrogenic effect when using a standardized extract. Chasteberry extract (Vitex agnus-castus) is well known for modulating FSH\/LH levels and alleviating premenstrual symptoms, and it also shows promise in reducing menopausal symptoms, particularly sleep disturbances. Dong Quai (Angelica sinensis) has long been used in traditional medicine to reduce the symptoms of menopause.\u003cbr\u003e\nThis natural substance was found to not only reduce menopausal symptoms in 85% of participants, but also improve cardiovascular risk factors, including LDL cholesterol, a concern for many perimenopausal women. Hesperidin, a citrus bioflavonoid derived from oranges, relieves vasomotor symptoms of menopause and has potent anti-inflammatory and metabolic benefits.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":41005597524053,"sku":"80041163","price":25.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/lhp8oihto8nt1fui8hiq.jpg?v=1739822208"},{"product_id":"estrovantage-em™","title":"EstroVantage EM™","description":"\u003cp\u003e- Offers a full range of protective compounds from cruciferous vegetables, including I3C, DIM and sulforaphane.\u003cbr\u003e\n- Provides a unique blend of herbs that improve estrogen metabolism, moving away from carcinogenic metabolites.\u003cbr\u003e\n- Promotes detoxification of a variety of environmental toxins as well as naturally produced hormones by enhancing phase 1 and phase 2 liver enzymes.\u003cbr\u003e\n- Contains plants with powerful anti-inflammatory activity.\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nEstroVantage EM provides a comprehensive formula of plant-derived compounds that improve the metabolism of estrogens and their metabolites. Cruciferous vegetables contain a variety of glucosinolates, which some studies have linked to a reduction in cancer incidence when consumed in larger quantities, most likely by causing a shift in metabolism toward less carcinogenic estrogen metabolites. EstroVantage EM contains indole-3-carbinol (I3C) and its metabolite 3,3'-diindolylmethane (DIM), as well as sulforaphane from broccoli powder, all of which have been associated with lower rates of neoplastic changes and a more favorable estrogenic profile. Not only do these glucosinolates improve estrogen metabolism, they also reduce inflammation by targeting key signaling molecules, such as Nrf2 and NF-κB.\u003cbr\u003e\nEstroVantage EM also contains other powerful plant compounds that reduce inflammation and block carcinogenic pathways. Silymarin, an extract of milk thistle, decreases the regulation of genetic products involved in the proliferation of tumor cells, as well as their invasion, angiogenesis and metastasis. This unique combination contains green tea polyphenols, lycopene (tomato extract), turmeric and rosemary extracts, as well as calcium D-glucarate, which has been shown to favorably modify estrogen metabolism and reduce carcinogenic risk. Just recently, a randomized, double-blind, placebo-controlled crossover study demonstrated that taking this formula resulted in significantly higher urinary levels of the protective estrogen metabolite 2-OHE1 and lower levels of the more dangerous estrogen metabolite 16α-OHE1 in premenopausal women. More recently, a randomized, double-blind, placebo-controlled crossover study demonstrated that taking this formula resulted in significantly higher urinary levels of the protective estrogen metabolite 2-OHE1 and lower levels of the more dangerous estrogen metabolite 16α-OHE1 in premenopausal women.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":41005597556821,"sku":"80044252","price":41.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/c9x79fqqlf0xj5gylrth.jpg?v=1739822208"},{"product_id":"somno-pro®-l-theanine-5-htp-melatonin-tropical-breeze","title":"Somno-Pro® L-Theanine · 5-HTP · Melatonin · Tropical Breeze","description":"\u003cp\u003e- Addresses all facets of insomnia: difficulty falling asleep, difficulty maintaining sleep, waking up too early in the morning and difficulty waking up.\u003cbr\u003e\n- Reduces nervous system excitement, which can inhibit sleep\u003cbr\u003e\n- Contains Suntheanine®, the most clinically studied L-theanine\u003cbr\u003e\n- Delicious chewable tablets with tropical fruit flavor\u003cbr\u003e\nL-theanine, 5-hydroxytryptophan (5-HTP), and melatonin have been shown to independently improve the quality and quantity of sleep and\/or decrease anxiety. L-theanine is an amino acid found almost exclusively in tea, which influences the central nervous system through a number of mechanisms, primarily by influencing levels of the neurotransmitters dopamine, gamma-aminobutyric acid (GABA), serotonin, norepinephrine and glutamate. These effects cause a significant increase in alpha brainwave activity, indicating a state of awake relaxation, increased performance under stress, improved learning and concentration, and decreased anxiety.\u003cbr\u003e\n5-HTP is the intermediary between L-tryptophan and serotonin, a key neurotransmitter associated with sleep, mood and anxiety. 5-HTP bypasses the rate-limiting enzyme tryptophan hydroxylase, which normally limits the conversion of tryptophan to serotonin.\u003cbr\u003e\nMelatonin is also closely related and is formed by the conversion of serotonin in the pineal gland in low light conditions. Known to regulate many biological rhythms, including the circadian cycle, melatonin has shown clinical benefits for inducing sleep or adjusting sleep cycles. Randomized trials have shown that it reduces sleep onset latency and improves perceived sleep quality, without altering daytime psychomotor performance.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Tablets Croquables","offer_id":41085436395605,"sku":"somno-pro-bioclinic-naturals-90-comprime-croquable","price":32.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/in2amm8kz9dxeebtgfex.jpg?v=1739822206"},{"product_id":"sereni-pro™","title":"Sereni-Pro™","description":"\u003cp\u003e- Anti-stress adaptogens and antioxidants restore and revitalize the body's glands and organs in isolated and chronic stressful conditions.\u003cbr\u003e\n- Herbal formula contains no glandular extracts\u003cbr\u003e\n- Provides broad-spectrum help for a variety of stress-related disorders\u003cbr\u003e\n- Safe, non-addictive and can be used long term\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nAshwagandha (Withania somnifera), Siberian ginseng (Eleutherococcus senticosus), lavender (Lavandula angustifolia), and rhodiola (Rhodiola rosea) are herbs known for their adaptogenic and calming properties, as well as for alleviating the effects of stress and fatigue. Adaptogens induce protective benefits against stress facilitated by the regulation of homeostasis via several molecular networks, including modulation of the hypothalamic-pituitary-adrenal axis and the expression of several stress-related proteins, including neuropeptide Y.\u003cbr\u003e\nAshwagandha limits the production of dopamine and other hormones in response to stress and also acts as a GABA receptor agonist, all of which have the effect of reducing the overall stress response. In controlled trials, it improved memory and several markers of cognitive function in individuals. with mild cognitive impairment, as well as reduced cortisol, stress and anxiety in stressed healthy adults. Siberian ginseng root contains eleutherosides, known to have anti-fatigue, anti-stress and immunomodulatory effects, and have been clinically shown to have therapeutic effectiveness against chronic fatigue and stress, as well as to improve sports performance. Lavender oil is believed to act on both the central and sympathetic nervous systems, and has been clinically shown to have a calming and relaxing effect, promoting an improvement in sensations. of well-being. Rhodiola rosea has been clinically shown to improve attention, cognitive function and mental performance, decrease the cortisol response to stress, exert an anti-fatigue effect, improve anaerobic exercise performance and improve mood. effect of SSRIs with a favorable safety profile.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":41005597655125,"sku":"sereni-pro-bioclinic-naturals-90c","price":23.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/edpgcxq2ampcfzoadb8o.jpg?v=1739822206"},{"product_id":"same-200-mg","title":"SAMe · 200 mg","description":"\u003cp\u003e- Relieves osteoarthritis pain\u003cbr\u003e\n- Key factor in several biological pathways including methylation reactions, glutathione formation and glutathione S-transferase activity\u003cbr\u003e\n- Enteric coating protects SAMe degradation caused by stomach acid, allowing for significantly improved intestinal absorption.\u003cbr\u003e\n- 200 mg SAMe per tablet for flexible dose titration\u003cbr\u003e\n- SAMe is produced through a natural fermentation process that produces higher active ingredients than synthetic variations.\u003cbr\u003e\n- Suitable for vegetarians\u003cbr\u003e\nS-Adenosyl-L-Methionine (SAMe) has several essential physiological functions and is the common thread between three key metabolic pathways. Well recognized as a unique methyl donor for over 100 biological reactions, including DNA methylation. It also links methylation to the synthesis of polyamines (necessary for cell survival and growth) and transsulfuration, which is responsible for the production of cysteine, the limiting factor in glutathione synthesis. Its unique positioning within these crossed pathways explains its role as regulator of redox status, cellular metabolism, proliferation and apoptosis.\u003cbr\u003e\nIt has been clinically proven to relieve a number of conditions, including osteoarthritis, fibromyalgia, neurodegenerative diseases, depression and liver disease. For patients with major depressive disorder, SAMe has been shown to be effective not only compared to standard antidepressants, but also for non-responders to selective serotonin reuptake inhibitors (SSRIs). It has also been shown to reduce the incidence of sexual dysfunction that commonly accompanies SSRI\/SNRI treatment. SAMe has also shown effectiveness for osteoarthritis comparable to that of NSAIDs, including celecoxib. More importantly, this is likely due to an increase in cartilage formation, glutathione production, DNA methylation, and gene expression that contribute to its effectiveness, a stark contrast to pharmaceutical painkillers. Research also suggests benefit for neurodegenerative diseases and potentially for improving endothelial function.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"30 Tablets","offer_id":41085436297301,"sku":"same-bioclinic-naturals-30c","price":29.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/t78uhkkxptxkzns3vpqv_7c07bfaf-3c4f-4ff5-86cb-6f04b051541f.jpg?v=1739822205"},{"product_id":"nmn","title":"NMN","description":"\u003cp\u003e- Provides 150 mg of nicotinamide mononucleotide (NMN) per serving, which has been shown in clinical trials to increase blood levels of NAD+.\u003cbr\u003e\n- NMN is the immediate precursor of NAD+ and compensates for the age-related decline in NAD+ levels.\u003cbr\u003e\n- NAD+ is an essential coenzyme for many pathways related to energy production, mitochondrial health, and DNA repair, and its decline is strongly associated with aging.\u003cbr\u003e\n- Vegetarian capsules with clinically established dosage\u003cbr\u003e\nNMN is a bioavailable precursor of nicotinamide adenine dinucleotide (NAD+), a key coenzyme necessary for more than 500 enzymatic reactions. As many of these enzymatic reactions are linked to cellular metabolism, aging, inflammation, circadian rhythm, mitochondrial respiration, glycolysis and DNA repair, NAD+ is considered essential for human health and longevity. NAD+ is also necessary for the expression of sirtuins, enzymes with numerous cellular regulatory effects that are particularly important for inflammation, DNA repair, and energy metabolism. Much research shows that aging causes a decrease in the expression of NAD+ and sirtuins, which leads to impaired mitochondrial function and biogenesis and increased oxidative damage, drivers of the aging process itself as well as many diseases associated with aging, including cardiovascular and metabolic diseases.\u003cbr\u003e\nControlled clinical trials have demonstrated multiple benefits of NMN supplementation, including improving insulin sensitivity and signaling in women with impaired glucose metabolism, as well as aerobic capacity in healthy runners, reducing sleepiness, and improving sitting posture in older adults.6-8 To illustrate its potential to act on aging pathways by restoring NAD+ levels, NMN supplementation during 12 weeks showed a trend toward reduction in arterial stiffness, an independent age-related risk factor for cardiovascular and metabolic diseases.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":41005597884501,"sku":"80121612","price":58.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/zfoddjsu6scwfxi6yrh1.jpg?v=1739822203"},{"product_id":"mitochondrial-formula","title":"Mitochondrial Formula","description":"\u003cp\u003e- Increases cellular energy\u003cbr\u003e\n- Provides a high dose of clinically relevant key nutrients, including 300 mg of CoQ10 and 1500 mg of acetyl-L-carnitine.\u003cbr\u003e\n- Contains a combination of sustainably manufactured ancient peat and apple extracts, which have been shown to increase levels of ATP, the primary source of cellular energy, without increasing reactive oxygen species.\u003cbr\u003e\n- The antioxidant protection of superoxide dismutase and L-glutathione Opitac® ensures redox balance within the cell.\u003cbr\u003e\n- Without stimulant\u003cbr\u003e\n- Suitable for vegetarians, with easy dosing and natural watermelon flavor for the powder version\u003cbr\u003e\nMitochondrial Formula is a unique combination of nutrients designed to improve mitochondrial function by increasing ATP production, while providing intracellular antioxidant protection. Mitochondria are the energy plants of the cell. They consume 80 to 90% of the cell's oxygen to produce ATP through the process of oxidative phosphorylation (OXPHOS). Alteration of mitochondrial bioenergy is at the origin of the aging process and many chronic cardiovascular, metabolic and neurological conditions. Acetyl-L-carnitine shuttles fatty acids and the mitochondrial membrane, which is essential for generating energy through fatty acid metabolism. It has been shown to improve fatigue, neurological and cognitive functions, and blood pressure. The antioxidant CoQ10 is a component of the mitochondrial respiratory chain and an essential cofactor of the electron transport system. It has shown clinical benefits in many conditions, including hypertension and migraine.\u003cbr\u003e\nElevATP™ is a blend of plant bio-inorganic trace elements and an apple extract rich in polyphenols such as rocyanidins and chlorogenic acid. It has been shown to increase whole blood ATP levels as well as exercise performance and body composition, without an increase in reactive oxygen species. Since mitochondria are the primary source of free radical production within a cell, bioavailable L-glutathione Opitac® and superoxide dismutase (from Extramel®) are also key components. They are essential for redox balance within a cell and have been shown to reduce the perception of stress and fatigue.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"81g","offer_id":41005597982805,"sku":"80091247","price":57.99,"currency_code":"CAD","in_stock":true},{"title":"120 Capsules","offer_id":41005598015573,"sku":"80116941","price":56.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/xtaya1flowbtcrhw2q7i.jpg?v=1739822203"},{"product_id":"melatonin-10-mg","title":"Melatonin · 10 mg","description":"\u003cp\u003e- Sublingual tablets provide rapid and superior absorption of melatonin, bypassing hepatic and gastrointestinal metabolism - pharmacokinetic studies indicate that 30-60% of an oral dose of melatonin is metabolized by the liver1 and that overall gastrointestinal absorption is variable.\u003cbr\u003e\n- A single high potency sublingual tablet is optimal for people who need higher doses of melatonin (10-20 mg).\u003cbr\u003e\n- Derived from non-animal sources\u003cbr\u003e\n- Natural and refreshing peppermint aroma\u003cbr\u003e\n- Does not cause addiction\u003cbr\u003e\nSleep is an essential part of health and many of us don't get enough of it. The 2002 Canadian Community Health Survey found that about 1 in 7 adults have difficulty falling or staying asleep. Insomnia affects one in three older adults and is 40% more common in women. Changes in sleep patterns are largely a reflection of our circadian rhythms, which are guided by the pineal hormone melatonin. Melatonin is known to decline with age, which explains a number of the sleep changes observed throughout life. Additionally, jet lag and shift work can significantly alter circadian rhythms and therefore melatonin secretion.\u003cbr\u003e\nMelatonin has been shown to be clinically beneficial for inducing sleep or adjusting sleep cycles, reducing time to sleep onset, and improving perceived sleep quality, without impairing daytime psychomotor performance. In fact, melatonin supplement and light therapy are considered standard medical treatment for jet lag, shift work, age-related insomnia, delayed sleep phase disorder, advanced sleep phase disorder, and 24-hour sleep-wake disorder. Chronic sleep disorders are a risk factor for premature aging, diabetes, obesity, cardiovascular disease and certain cancers, showing how important it is to maintain normal melatonin levels to improve sleep quality.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"180 Tablets Sublinguals","offer_id":41085436166229,"sku":"80036635","price":42.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/jx1k1qs4f1kyhof0dsuz.jpg?v=1739822201"},{"product_id":"melatonin-3-mg","title":"Melatonin · 3 mg","description":"\u003cp\u003e- Sublingual tablets provide rapid and superior absorption of melatonin, bypassing hepatic and gastrointestinal metabolism - pharmacokinetic studies indicate that 30-60% of an oral dose of melatonin is metabolized by the liver1 and that overall gastrointestinal absorption is variable\u003cbr\u003e\n- The 3 mg concentration is optimal for people who need basic sleep support or who are trying melatonin for the first time.\u003cbr\u003e\n- Derived from non-animal sources\u003cbr\u003e\n- Natural and refreshing peppermint aroma\u003cbr\u003e\n- Does not cause addiction\u003cbr\u003e\nSleep is an essential part of health and many of us don't get enough of it. The 2002 Canadian Community Health Survey found that about 1 in 7 adults have difficulty falling or staying asleep. Insomnia affects one in three older adults and is 40% more common in women. Changes in sleep patterns are largely a reflection of our circadian rhythms, which are guided by the pineal hormone melatonin. Melatonin is known to decline with age, which explains a number of the sleep changes observed throughout life. In addition, jet lag and shift work can significantly alter circadian rhythms and therefore melatonin secretion.\u003cbr\u003e\nMelatonin has been shown to be clinically beneficial for inducing sleep or adjusting sleep cycles, reducing time to sleep onset, and improving perceived sleep quality, without impairing daytime psychomotor performance. In fact, melatonin supplement and light therapy are considered standard medical treatment for jet lag, shift work, age-related insomnia, delayed sleep phase disorder, advanced sleep phase disorder, and 24-hour sleep-wake disorder. Chronic sleep disorders are a risk factor for premature aging, diabetes, obesity, cardiovascular disease and certain cancers, showing how important it is to maintain normal melatonin levels to improve sleep quality.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"180 Tablets Sublinguals","offer_id":41085436133461,"sku":"80036632","price":14.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/cyfxghxklub9khzvdbg2.jpg?v=1739822201"},{"product_id":"gaba-pro®-100-mg","title":"GABA-Pro® · 100 mg","description":"\u003cp\u003e- Improves calm and relaxation during daily stress, reduces the negative effects of caffeine consumption and complements other anti-stress supplements.\u003cbr\u003e\n- Fast acting, effects can be felt in just five minutes and last four to six hours.\u003cbr\u003e\n- GABA-Pro uses Pharma GABA, the natural form of GABA which is superior to the synthetic form. It is made naturally through a fermentation process that uses Lactobacillus hilgardii, the bacteria used to ferment vegetables in the traditional Korean dish, kimchi.\u003cbr\u003e\n- Gentle and non-addictive, it has virtually no side effects.\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nGamma-amino-butyric acid (GABA) is one of the main inhibitory neurotransmitters in the central nervous system, balancing the excitatory effects of glutamate on neuronal activity. The inhibitory effects of GABA are generally considered to decrease anxiety, release muscle tension, and have sedative-like effects. Additionally, conditions such as anxiety, depression, insomnia, and epilepsy have all been associated with low GABA concentration or activity. GABA has also been shown to cause a significant increase in alpha brain waves compared to control, indicating a more relaxed state, as well as improved concentration. In a clinical trial involving patients with vertigo, GABA-Pro was found to increase salivary IgA levels when crossing a suspension bridge, compared to the control group whose salivary IgA levels dropped by 35%.4 This demonstrates the stress-reducing effect of GABA-Pro.\u003cbr\u003e\nIncreasing GABA activity is also a therapeutic target for many drugs used in the treatment of insomnia, often by targeting GABA receptors. This has the effect of reducing the number of awakenings, shortening sleep latency and increasing slow-wave sleep.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":41005598179413,"sku":"80051092","price":33.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/xeldoqmrs6ghbhwq2e4a.jpg?v=1739822200"},{"product_id":"gaba-pro®-100-mg-tropical-breeze","title":"GABA-Pro® · 100 mg Tropical Breeze","description":"\u003cp\u003e- Uses Pharma GABA™, a naturally occurring form of GABA.\u003cbr\u003e\n- Made naturally through a fermentation process that uses Lactobacillus hilgardii, the bacteria used to ferment vegetables in the preparation of kimchi, the traditional Korean dish.\u003cbr\u003e\n- Improves calm and relaxation in the face of daily stress, soothes nervous tension and reduces the negative effects of caffeine consumption, without causing drowsiness.\u003cbr\u003e\n- Fast acting - effects can be felt in as little as five minutes and last four to six hours1\u003cbr\u003e\n- Generally Recognized as Safe (GRAS) product status in the United States.\u003cbr\u003e\n- Delicious chewable tablet with tropical fruit flavor\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nGamma-aminobutyric acid (GABA) is one of the main inhibitory neurotransmitters of the central nervous system, balancing the excitatory effects of glutamate on neuronal activity. The inhibitory effects of GABA are generally considered to decrease anxiety, release muscle tension, and have sedative-like effects. GABA has also been shown to cause a significant increase in alpha brain waves, which are associated with a more relaxed state and improved concentration.\u003cbr\u003e\nIn a clinical trial involving people with fear of heights, a control group crossing a suspension bridge recorded a 35% drop in salivary levels of secretory immunoglobulin A (sIgA), a marker of stress-related declines in immune system activity. Participants who crossed the same bridge, but took GABA-Pro, saw their secretory immunoglobulin A levels increase, suggesting a stress-reducing effect.\u003cbr\u003e\nMany medications used to treat insomnia also target GABA receptors and activity, with effects such as decreasing arousal, shortening sleep latency, and increasing slow-wave sleep.\u003cbr\u003e\nPharma GABA is well absorbed and binds to GABA receptors in the peripheral nervous system (PNS), the branch of the autonomic nervous system (ANS) responsible for producing the \"relaxation response\" - the opposite of the \"fight or flight\" response. In a double-blind crossover study, 12 young adult men taking 30 mg of Pharma GABA per meal after an overnight fast experienced significant increases in overall ANS and PNS activities, compared to placebo. This suggests that Pharma GABA may induce relaxation effects by modulating ANS activity.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Tablets Croquables","offer_id":41085436100693,"sku":"80052082","price":37.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/ykyzgardpcogdkp4fmh3.jpg?v=1739822199"},{"product_id":"cortalign™-stress-manager","title":"CortAlign™ Stress Manager","description":"\u003cp\u003e- Promotes temporary relaxation and increases resistance to stress and anxiety\u003cbr\u003e\n- Provides adaptogenic protection against various stressors\u003cbr\u003e\n- Herbal formula, without glandular extracts\u003cbr\u003e\n- Standardized plant ingredients provide 5% withanolides (ashwagandha), 8.5% honokiol (magnolia) and 2.1% berberine (phellodendron).\u003cbr\u003e\n- Each tablet contains clinical doses of medicinal plants\u003cbr\u003e\n- Suitable for vegetarians\u003cbr\u003e\nCortAlign contains a unique variety of herbs and nutrients that have been shown to have a moderating effect on stress and anxiety, and to normalize cortisol secretion. Ashwagandha has a number of adaptogenic effects, including modulation of GABA receptors, which is partly responsible for the significant reduction in anxiety and stress demonstrated in clinical trials. The KSM-66TM formulation of ashwagandha in particular has been shown to reduce serum cortisol levels by 27% and improve markers of depression, stress and anxiety compared to a placebo.\u003cbr\u003e\nThe combination of magnolia and phellodendron (Relora®blend) helps reduce stress and anxiety, and has been shown to reduce salivary cortisol levels and perception of stress, improve other mood parameters, and prevent stress-related weight gain compared to placebo. Phosphatidylserine plays a critical role in the structure and function of neuronal cells and has been shown to dampen the stress response, improve mood, and normalize cortisol release.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"30 Tablets","offer_id":41085436035157,"sku":"80064503-30c","price":27.99,"currency_code":"CAD","in_stock":true},{"title":"90 Tablets","offer_id":41085436067925,"sku":"80064503","price":67.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/iuekf62wfhmvrgyfttbu.jpg?v=1739822199"},{"product_id":"calm-pro™-100-mg-tropical-breeze","title":"Calm-Pro™ · 100 mg · Tropical Breeze","description":"\u003cp\u003e- Reduces stress and anxiety and restores a calm mental state\u003cbr\u003e\n- Contains Suntheanine®, a pure form of L-theanine, produced by a patented enzymatic process that produces 100% pure L-isomeric theanine.\u003cbr\u003e\n- Suntheanine is the most clinically studied L-theanine.\u003cbr\u003e\n- Delicious chewable tablets with tropical fruit flavor\u003cbr\u003e\nL-theanine is an amino acid naturally found in tea. It has been shown to have a calming effect on the brain, triggering the production of alpha brain waves associated with a state of wakefulness and relaxation, and decreasing beta brain waves associated with feelings of agitation and nervousness. L-theanine influences levels of the neurotransmitters dopamine, serotonin, norepinephrine and glutamate, and is also metabolized to gamma-aminobutyric acid (GABA), a neurotransmitter that plays a key role in relaxation and memory.\u003cbr\u003e\nL-theanine may help temporarily promote relaxation and improve feelings of stress. In one study, a group of 50 women aged 18 to 22 were divided into two groups: a high-anxiety group and a low-anxious group. They were given either water (as a control) or a solution containing 50 mg or 200 mg of L-theanine, and their brain waves were measured for 60 minutes. Compared to controls, the group receiving 200 mg of L-theanine had a significant increase in alpha brain waves, indicating a relaxation effect. Similar results were seen in another clinical trial where 35 healthy young volunteers were given 50 mg of L-theanine and experienced elevated alpha brain wave activity for the next 105 minutes.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Tablets Croquables","offer_id":41085436002389,"sku":"80020918","price":32.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/lqumr8dnzwd1hqxanuun.jpg?v=1739822198"},{"product_id":"theracurmin™-2x-120-mg","title":"Theracurmin™ 2X · 120 mg","description":"\u003cp\u003e- Theracurmin 2X has the highest concentration of Theracurmin curcumin per capsule available\u003cbr\u003e\n- Smaller capsules, more concentrated potency\u003cbr\u003e\n- Uses patented natural colloidal dispersion technology to improve bioavailability and significantly increase blood curcumin levels\u003cbr\u003e\n- Advanced manufacturing techniques increase blood levels of free curcumin in a linear dose-dependent relationship\u003cbr\u003e\n- Curcumin modulates an impressive number of molecular targets – enhanced absorption allows for significantly greater potency and therapeutic effect.\u003cbr\u003e\n- High potency formula allows for easy dosing\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nCurcumin's role in preventing atherosclerotic plaque formation, platelet aggregation, and LDL oxidation indicates multiple cardiovascular benefits and its ability to inhibit angiogenesis and induce apoptosis in cancer cells suggests both preventive and therapeutic benefits. Prospective clinical trial data also showed the effectiveness of Theracurmin in relieving symptoms of knee osteoarthritis and decreasing the need for rescue medications.\u003cbr\u003e\nThe limiting factor in the effectiveness of curcumin is its low systemic bioavailability, as it is poorly absorbed in the gastrointestinal tract and rapidly metabolized. The advanced manufacturing techniques used to make Theracurmin have reduced its particle size by more than 100 times, and the combined use of natural substances like emulsifiers to form a colloidal suspension have significantly increased the bioavailability of curcumin. This significantly increases blood levels of curcumin, several times higher than other preparations, including so-called enhanced forms of curcumin. Theracurmin increases curcumin levels in a linear, dose-dependent manner, circumventing previous limitations of curcumin supplementation to achieve unprecedented curcumin blood levels. Detailed absorption studies have proven that Theracurmin is the best absorbed form of curcumin on the market.\u003cbr\u003e\nA scientific review found that Theracurmin was more bioavailable, milligram for milligram, than other enhanced and regular forms of curcumin.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"75 Capsules","offer_id":41005598802005,"sku":"theracurmin-2x-bioclinic-naturals-75c","price":70.99,"currency_code":"CAD","in_stock":true},{"title":"30 Capsules","offer_id":41005598834773,"sku":"theracurmin-2x-bioclinic-naturals-30c","price":31.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/yj6uvlqwq7d4zuu5rr4g.jpg?v=1739822197"},{"product_id":"dolor-ease","title":"Dolor Ease","description":"\u003cp\u003e- Complete formula including white willow (Salix alba) extract (bark), devil's claw, Theracurmin curcumin extract and boswellia extract (Boswellia serrata).\u003cbr\u003e\n- Used in herbal medicine for short-term relief of lower back pain.\u003cbr\u003e\n- Traditionally used to relieve minor joint pain caused by osteoarthritis.\u003cbr\u003e\n- Contains 30 mg of Theracurmin, the most bioavailable form of curcumin, which provides natural antioxidant and anti-inflammatory support.\u003cbr\u003e\n- Includes InflamRelief, a natural source of antioxidants to protect joint tissues.\u003cbr\u003e\n- Promotes joint health and comfort\u003cbr\u003e\nDolor Ease is a comprehensive formula that contains some of the best-known natural extracts used in herbal medicine to support joint health and temporarily relieve joint pain related to osteoarthritis.\u003cbr\u003e\nWhite willow bark contains compounds such as salicin (chemically similar to aspirin) which have anti-inflammatory and analgesic effects. Research shows that white willow bark may be effective in providing short-term relief from lower back and joint pain related to osteoarthritis.\u003cbr\u003e\nDevil's claw also contains compounds that preliminary research shows inhibit the inflammatory cascade. This extract has long been used in herbal medicine to help relieve joint pain associated with osteoarthritis.\u003cbr\u003e\nTheracurmin is a highly bioavailable form of curcumin‡, a natural compound with anti-inflammatory and antioxidant properties. Standard curcumin is poorly absorbed, but Theracurmin is produced using innovative proprietary technology to create small curcumin particles that significantly increase bioavailability.\u003cbr\u003e\nDolor Ease also contains InflamRelief, a source of antioxidants that help protect cells and joint tissues from oxidative damage, as well as boswellia, a plant extract used in herbal medicine to support joint health.\u003cbr\u003e\nThe scientific review found that Theracurmin was more bioavailable, milligram for milligram, than other enhanced or regular forms of curcumin.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"120 Capsules","offer_id":41005598933077,"sku":"80054434","price":40.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/ozma2l90qlukaei7wlll.jpg?v=1739822195"},{"product_id":"l-glutamine-with-theracurmin™","title":"L-Glutamine with Theracurmin™","description":"\u003cp\u003e- Provides 5g of L-glutamine and 30mg of Theracurmin per serving\u003cbr\u003e\n- Targets multiple pathways of inflammation and protein synthesis to improve muscle repair and recovery after exercise.\u003cbr\u003e\n- Provides support for the immune and digestive systems\u003cbr\u003e\n- Theracurmin has higher bioavailability and faster absorption in humans, compared to standard curcumin1,2.\u003cbr\u003e\n- The powder formulation allows flexible and convenient dosing.\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nL-glutamine combined with Theracurmin provides two complementary nutrients that target inflammation and support gut and musculoskeletal health, particularly in response to exercise. L-glutamine is the most abundant amino acid in the body, an intermediate of the Krebs cycle that is particularly important for intestinal and immune cells, and is known to be depleted following intense physical activity. L-glutamine supplementation has been shown to prevent exercise-induced increases in intestinal permeability, by promoting tight junction stability, increasing the production of anti-inflammatory cytokines, and suppressing inflammation, including NF-κB activation. L-glutamine also stimulates protein synthesis pathways while inhibiting protein breakdown, and has been shown to improve muscle recovery, reduce muscle soreness, and limit muscle damage after exercise.\u003cbr\u003e\nCurcumin has well-established anti-inflammatory effects on multiple molecular targets, including NF-κB, as well as cyclooxygenases and lipoxygenases, and it also promotes the restoration of intestinal integrity by enhancing the expression of tight junction proteins. Curcumin supplementation has been shown to alleviate damage to muscles after exercise, reduce pain from late onset soreness, and improve muscle performance recovery. Theracurmin, in particular, has been shown to prevent both increases in creatine kinase and muscle breakdown after eccentric exercise. In a prospective clinical trial, theracurmin was found to be effective in relieving symptoms and reducing the need for rescue medications in participants with knee osteoarthritis. Both L-glutamine and theracurmin target multiple mechanisms associated with inflammation, muscle repair, and muscle function.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"306 g","offer_id":41005598998613,"sku":"80065236","price":40.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/phlns3nc0lsqyomvuxi7.jpg?v=1739822194"},{"product_id":"prefoundation™-prenatal-multiple-vitamin-mineral-formula","title":"PreFoundation™ Prenatal Multiple Vitamin \u0026 Mineral Formula","description":"\u003cp\u003e- Provides highly bioavailable forms and clinical doses of essential vitamins and minerals for optimal prenatal health.\u003cbr\u003e\n- Contains vitamins D3, K2 (menaquinone-7) and folate in the form of L-5-MTHF - key prenatal vitamins whose forms have been shown to be superior to those typically used in prenatal formulas.\u003cbr\u003e\n- Provides citrate forms of key minerals, including magnesium, calcium, zinc and copper, as well as 5'-phosphate forms of riboflavin and vitamin B6, and iron bisglycinate.\u003cbr\u003e\nPreFoundation provides a complete prenatal multivitamin\/mineral, with optimal dosing and bioavailable forms of each nutrient. Vitamin D3 has been shown to restore vitamin D levels more effectively than vitamin D2, with higher maternal vitamin D levels being linked to a lower risk of ADHD, and supplementation being linked to a lower risk of wheezing in the child and higher birth weight\/length. PreFoundation also provides L-5-MTHF, the bioactive form of folate, which bypasses the often impaired enzymatic step necessary for folic acid activation. Therefore, pregnant women taking an L-5-MTHF supplement have been shown to have higher red blood cell folate levels than when they took a folic acid supplement. Better executive function was also observed in children whose mothers took a 5-MTHF supplement during pregnancy.\u003cbr\u003e\nPotassium iodide is an essential source of iodine, often deficient in women, but linked to the cognitive development of children. Vitamin K2, in the form of menaquinone-7, is known to have a longer half-life than other forms of vitamin K, and has been associated with greater carboxylation of osteocalcin in children, which is essential for optimal bone health. PreFoundation also provides highly bioavailable forms of other vitamins and minerals essential for prenatal health, including bioavailable citrate forms of calcium, magnesium, zinc and copper, as well as the bisglycinate form of iron, which has been shown to be as effective during pregnancy as twice the dose of iron typically used. PreFoundation also provides higher forms of B vitamins, including vitamin B12 in the form of methylcobalamin, and the 5'-phosphate forms of riboflavin and vitamin B6.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":41005599293525,"sku":"prefoundation-bioclinic-naturals-90c","price":32.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/drum6wdghtsjwd646j76.jpg?v=1739822190"},{"product_id":"magnesium-bisglycinate-200-mg","title":"Magnesium Bisglycinate 200 mg","description":"\u003cp\u003e- The bisglycinate form of magnesium is more easily absorbed than salt forms such as magnesium oxide1\u003cbr\u003e\n- The chelated form of bisglycinate is less likely to cause laxative effects than the saline forms1,2.\u003cbr\u003e\n- The powder form allows easy and practical dosing away from food.\u003cbr\u003e\n- The vegetable capsules provide 200 mg of elemental magnesium per capsule.\u003cbr\u003e\n- Non-GMO and suitable for vegetarians\/vegans\u003cbr\u003e\n- Sugar-free, with a pleasant taste due to citric acid for the powder version\u003cbr\u003e\nMagnesium contributes to the proper functioning of muscles. It also supports metabolism, which is the ability to obtain energy from proteins, carbohydrates and fats. Magnesium helps normalize blood pressure and fasting blood sugar, improve insulin sensitivity and reduce the risk of developing type 2 diabetes mellitus, while reducing blood pressure, hyperglycemia and triglycerides in metabolic syndrome. Magnesium requirements can be increased by stress, an unbalanced diet, coffee and alcohol consumption, and certain medications such as proton pump inhibitors. Therefore, it can be difficult to meet the body's daily magnesium requirements through diet alone.\u003cbr\u003e\nIn a randomized, controlled trial, healthy older women were assigned to a treatment group receiving 300 mg of magnesium per day or a control group. After 12 weeks, the treated group showed significant improvements in physical performance compared to the control group. The authors concluded that supplementation may play a role in preventing age-related physical decline. A double-blind, placebo-controlled trial showed that supplementing with 300 mg of magnesium bisglycinate daily for four weeks decreased the frequency and intensity of pregnancy-induced leg cramps. Magnesium is an important factor in muscle mass and repair, and has been shown to relieve muscle cramps from a variety of causes.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"145 g","offer_id":41005599359061,"sku":"80090179","price":20.99,"currency_code":"CAD","in_stock":true},{"title":"120 Capsules","offer_id":41005599391829,"sku":"80075249","price":26.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/uf7hfl36yxmoxf3bvh9p.jpg?v=1739822189"},{"product_id":"liposomal-vitamic-c","title":"Liposomal Vitamin C","description":"\u003cp\u003e- 1000 mg of vitamin C per serving of two softgels\u003cbr\u003e\n- Liposomes encapsulate vitamin C in a highly bioavailable lipid bilayer, exceeding plasma levels of standard supplements.\u003cbr\u003e\n- Liposomes increase both peak plasma concentrations and total absorption of vitamin C.\u003cbr\u003e\n- Mild form of vitamin C\u003cbr\u003e\n- Powerful antioxidant, also providing support for the immune system, collagen and bones\u003cbr\u003e\n- GMO and gluten free\u003cbr\u003e\nLiposomal vitamin C is a highly bioavailable form of this essential antioxidant known to protect against oxidative damage, support healthy immune function, and play an essential role in collagen synthesis. Vitamin C is a cofactor for prolyl and lysyl hydroxylases, enzymes necessary for the development of collagen in joints and bones. High vitamin C intake has been associated with a reduced risk of osteoporotic fracture and an increase in bone mineral density. Vitamin C increases iron absorption, stabilizes vitamin E and folate, and reduces inflammation. An increased risk of deficiency has been identified in a number of populations, including older adults, people with inflammatory bowel disease, cancer or food allergies, and tobacco smokers. Vitamin C supplementation boosts immune function and is associated with a shorter duration of respiratory tract infections, such as the common cold. Supplementation has also been associated with improved liver function and blood sugar control in nonalcoholic fatty liver disease (NAFLD).\u003cbr\u003e\nLiposomes encapsulate vitamin C in a phospholipid bilayer, thereby circumventing the usual limitations of absorption and increasing plasma ascorbic acid levels to a greater extent than conventional supplementation. 8,9 Liposomal forms of vitamin C have been shown to nearly double the bioavailability while maintaining the safety of standard ascorbic acid supplementation.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Softgels","offer_id":41085435838549,"sku":"80121161","price":20.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/ykcn6mrgpr2xoyspntcd.jpg?v=1739822188"},{"product_id":"iron-bisglycinate","title":"Iron Bisglycinate","description":"\u003cp\u003e- Provides a clinical dose of 45 mg of elemental iron per capsule.\u003cbr\u003e\n- The highly absorbable form, iron bisglycinate chelate, has greater bioavailability than standard forms.\u003cbr\u003e\n- Comparable to iron sulfate at ¼ to ½ the same dose of elemental iron\u003cbr\u003e\n- Bisglycinate iron chelate is significantly better tolerated than commonly used forms, which allows its continued use and improved effectiveness in replenishing iron stores.\u003cbr\u003e\n- Suitable for vegetarians and vegans\u003cbr\u003e\nIron deficiency remains the most common nutrient deficiency and the most common cause of anemia worldwide. Depleted iron stores impair mitochondrial function and cellular respiration even in the absence of anemia, particularly in metabolically active cells, contributing to symptoms ranging from fatigue and exercise intolerance to cognitive and cardiac impairment. In the majority of cases, the primary means of replenishing iron levels is oral iron supplementation, which is preferable to parenteral administration (injections) in the absence of serious symptoms or contraindications.\u003cbr\u003e\nIn contrast, iron bisglycinate chelate, consisting of two glycine molecules chelated with ferrous iron (Fe2+), demonstrated significantly greater bioavailability than standard forms of iron such as ferrous sulfate, ferrous fumarate, and polymaltose iron. This form is much better tolerated, allowing iron levels to be effectively restored using lower doses. For example, at ¼ to ½ the dose of ferrous sulfate, the iron chelate bisglycinate showed similar effects on hemoglobin, ferritin, and other markers of hematologic status in controlled trials, with improved tolerability. It has also been shown to be effective and well-tolerated in various patient populations, including pregnant women and children with celiac disease. 45 mg of elemental iron per capsule, higher than most formulations, is consistent with current recommendations for restoring depleted iron levels in pregnant women, although below the threshold typically associated with adverse effects.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":41005599457365,"sku":"80107078","price":17.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/whhqf6usgwal03roil3t.jpg?v=1739822187"},{"product_id":"enhanced-b-complex","title":"Enhanced B Complex","description":"\u003cp\u003e- Supports energy production, nutrient metabolism, liver function, immune function and red blood cell production.\u003cbr\u003e\n- Contributes to the health of hair, skin and nails\u003cbr\u003e\n- Contains a full spectrum of B vitamins in the most metabolically active forms, which do not require conversion by the liver for use.\u003cbr\u003e\n- Provides a clinically effective dose of the most active and bioavailable form of folate, Quatrefolic.\u003cbr\u003e\n- Each capsule also provides the most bioactive and bioavailable forms of each B vitamin, including methylcobalamin (B12), riboflavin 5'-phosphate (B2), and pyridoxal 5'-phosphate (B6).\u003cbr\u003e\n- Suitable for vegetarians and vegans\u003cbr\u003e\nBioclinic Naturals Enhanced B Complex is a once-daily formula that provides full-spectrum B vitamins in their most metabolically active forms. B vitamins are cofactors for many important mechanisms in the body, including nutrient metabolism, energy production, growth and development, and liver function. B vitamins also contribute to immunity, red blood cell production and iron metabolism, as well as healthy skin, hair and nails. This formula contains B vitamins in their active form, such as vitamins B12 (methylcobalamin) and B6 (pyridoxal 5'-phosphate), to support the functioning of the nervous system. It also contains 50 mg of choline and 400 mcg of folate (Quatrefolic). Additionally, this formula contains vitamins B1, B2, B5 and B6, as well as niacin, with added support from biotin and inositol. This convenient all-in-one B-complex is an ideal supplement to help support metabolism, energy and overall health.\u003cbr\u003e\nQuatrefolic is an active form of folate at the cellular level, the form found in the circulation and the only one that crosses the blood-brain barrier. It may also be the optimal form to prevent neural tube defects. It does not need to be converted to the active form by the enzyme methylene tetrahydrofolate reductase (MTHFR), which is known to exhibit common single nucleotide polymorphisms. Administration of quatrefolic acid was associated with higher peak levels of (6S)-5-MTHF than folic acid and calcium 5-MTHF, even in individuals with high-functioning MTHFR polymorphisms.\u003cbr\u003e\nMethylcobalamin is a cofactor for B12-dependent enzymes and has direct biological activity. Combined with other B vitamins, it reduces the risk of macular degeneration and migraines, with effectiveness sometimes modulated by MTHFR status.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":41005599490133,"sku":"80120273","price":22.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/g5o0kxc8zpmuqf1mr5em.jpg?v=1739822187"},{"product_id":"b12-methylcobalamin-1000-mcg","title":"B12 Methylcobalamin · 1000 mcg","description":"\u003cp\u003e- Methylcobalamin is the active form of vitamin B12 for maximum benefit.\u003cbr\u003e\n- Higher bioavailability than the most common form, cyanocobalamin, which does not convert to a sufficient amount of methylcobalamin to correct certain forms of anemia, neurological defects and aging1.\u003cbr\u003e\n- Reduces homocysteine ​​levels for protective effects on the cardiovascular system\u003cbr\u003e\n- Sublingual tablets provide rapid action directly into the bloodstream.\u003cbr\u003e\nVitamin B12 is the cofactor of enzymatic reactions with various physiological functions. It is necessary for the conversion of methylmalonyl CoA to succinyl CoA, as well as the conversion of homocysteine ​​to methionine by methionine synthase, which is then converted to S-adenosylmethionine. B12 deficiency leads to deficiencies in these two pathways, disrupting neurological function, including poor formation of myelin sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.\u003cbr\u003e\nMethylcobalamin, the major circulating form of B12 and the one that is transported to peripheral tissues, has been shown to reduce not only homocysteine, but also inflammatory factors and carotid artery plaque volume in stroke patients, as well as pain and neuropathy in diabetics. Because of its relationship with myelin production and neurological function, high dose B12 has been used in a variety of neurodegenerative diseases, including Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis.\u003cbr\u003e\nSome people, especially those with malabsorption or low dietary intake, are at higher risk of B12 deficiency. People with poor B12 absorption rely on passive absorption, which is typically 1% of the amount ingested. Therefore, high doses may be necessary for people with greater B12 needs, such as the elderly and those with neurodegenerative disorders.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Tablets Sublinguals","offer_id":41085435773013,"sku":"80026765","price":11.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/az9rmq6iocft3ljd6y7m.jpg?v=1739822186"},{"product_id":"berberine-hcl-500-mg","title":"Berberine (anciennement Berberine HCl) · 500 mg","description":"\u003cp\u003e- Provides 500 mg of berberine hydrochloride per capsule, the dose used in clinical trials for glucose and lipid control.\u003cbr\u003e\n- Hypoglycemic effects through multiple mechanisms, including improvement of insulin sensitivity\u003cbr\u003e\n- Favorable effects on blood lipids, including a reduction in triglycerides and total and LDL cholesterol 9\u003cbr\u003e\n- Activation of Nrf-2, a key regulator of antioxidant gene transcription and prevention of glucose-induced neurotoxicity.\u003cbr\u003e\n- Extract of Berberis vulgaris (European barberry)\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nTraditionally used for gastrointestinal symptoms, berberine has been shown to be a potent cardiometabolic adjuvant with varied benefits and mechanisms of action. It has hypoglycemic effects, via inhibition of alpha-glucosidase activity and an increase in insulin receptors in peripheral tissues, thereby improving insulin sensitivity. Furthermore, it activates Nrf2, a key regulator of cellular antioxidant defense, and attenuates glucose-induced neurotoxicity, suggesting therapeutic potential for diabetic neuropathy.\u003cbr\u003e\nIn controlled trials, it reduced HbA1c levels in diabetic participants with comparable effectiveness to metformin. In participants with metabolic syndrome, it was shown to reduce waist circumference and body weight, blood pressure, triglycerides, and improve insulin resistance compared to placebo, with similar benefits in women with PCOS. Berberine targets multiple cardiometabolic risk factors, as it has also been shown to reduce total cholesterol and LDL cholesterol in diabetic participants in several controlled trials. Additionally, a clinical trial comparing standard therapy with or without berberine in patients undergoing percutaneous coronary intervention showed improvements in several inflammatory markers, including C-reactive protein, IL-6, MMP-9, ICAM-1, and VCAM-1.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":41005599916117,"sku":"80051589","price":35.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/xxk11cpck2cj0oxzvvy9.jpg?v=1739822182"},{"product_id":"immunealign™","title":"ImmuneAlign™","description":"\u003cp\u003e- Provides a clinically established dose of ECHINAMIDE®, a formulation of Echinacea purpurea triple standardized for its active components (alkylamides, polysaccharides and cichoric acid levels) using the whole herb (roots and flowers).\u003cbr\u003e\n- ECHINAMIDE is extracted from certified organic echinacea grown in Canada, according to GLP and GMP standards from seed to shelf.\u003cbr\u003e\n- Exclusive blend of ECHINAMIDE and powerful antiviral plant extracts of lomatium, astragalus, reishi mushroom and licorice for a synergistic effect on immune function.\u003cbr\u003e\n- Easy to swallow soft capsules\u003cbr\u003e\n- Tincture allows for easy dosing, suitable for vegans\/vegetarians.\u003cbr\u003e\nThe antiviral formula offers a synergistic combination of five clinically validated plant extracts, standardized to ensure optimal potency and effectiveness. ECHINAMIDE is a well-established formulation of organically grown Echinacea purpurea, triple standardized to key constituents (alkylamides, cichoric acid, and polysaccharides) that have been shown to enhance immune function and significantly reduce cold symptoms in randomized clinical trials. ECHINAMIDE stimulates the non-specific immune system, increasing the total number of leukocytes, neutrophils, monocytes and natural killer cells. Its alkylamides have anti-inflammatory and immunomodulatory effects, in part by binding to cannabinoid receptors on immune cells. Polysaccharides and polyphenols induce cell-mediated immunity and help stabilize secretory IgA levels. Although meta-analyses generally support the use of echinacea as an antiviral, standardization of its key components is essential to ensure clinical benefit.\u003cbr\u003e\nThis powerful antiviral formula also contains extracts of lomatium and reishi mushroom, antiviral plants used traditionally for a long time. Reishi contains triterpenoids that inhibit both viral entry into the cell and viral replication, and lomatium has in vitro inhibitory effects on rotavirus and blocks the production of CXCL10, a key signaling molecule for influenza and other viral infections. Echinacea, licorice, and astragalus extracts have been shown to increase CD25 production and work synergistically to induce greater expression of CD69, two indicators of immune cell activation and regulation. The broad antiviral and adaptogenic properties of these herbs support their combined use to optimize immune function and support upper respiratory health.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Softgels","offer_id":41085435609173,"sku":"80046957","price":25.99,"currency_code":"CAD","in_stock":true},{"title":"50 ml","offer_id":41005600014421,"sku":"80046955","price":16.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/utnz7wgl1xwjb1qy63pd.jpg?v=1739822180"},{"product_id":"ashwagandha-600-mg","title":"Ashwagandha 600 mg","description":"\u003cp\u003e- Provides 600 mg per capsule of proprietary, clinically studied organic Ashwagandha™ KSM-66 extract.\u003cbr\u003e\n- Features dairy-free KSM-66 extract, made only from the roots of the plant, with randomized clinical trials documenting effectiveness and safety for a range of conditions.\u003cbr\u003e\n- Extracted using a proprietary water-based \"green chemistry\" process, without the use of alcohol or chemical solvents.\u003cbr\u003e\n- Standardized to 5% withanolides, providing various physiological benefits.\u003cbr\u003e\n- Suitable for vegetarians and vegans\u003cbr\u003e\nAshwagandha (Withania somnifera) has long been used as a foundational adaptogen in Ayurvedic medicine. It is known to have many benefits, including increased resistance to stress and anxiety, improved physical performance and immune function, and improved fertility, sleep and neurological function. Its diverse phytochemistry includes withanolides, sitoindosides, phenolic compounds, and flavonoids, which help explain its diverse physiological actions, ranging from cardio and neuroprotective effects to anti-inflammatory and anxiolytic effects.\u003cbr\u003e\nKSM-66 is a full-spectrum ashwagandha extract that uses only the roots of the plant, notable for the large number of randomized, controlled trials that document its effectiveness. Clinical trials have demonstrated significant improvement in symptoms and cortisol levels in participants with chronic stress, as well as improved weight control and food cravings in this population. It has also been shown to improve general well-being, sleep quality and mental alertness in older adults, as well as memory and executive functions in people with cognitive impairment. Clinical trials document increased cardiorespiratory endurance, measured by VO2 max, in male and female athletes using KSM-66, as well as greater increases in muscle mass and strength when combined with resistance training. Additionally, KSM-66 extract has demonstrated benefits in improving sleep quality, improving sexual function in both men and women, restoring spermatogenic activity in oligospermic men, and improving thyroid function in individuals with subclinical hypothyroidism.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":41005600243797,"sku":"80116512","price":28.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/pnmo6unqhpxiauuvblmg.jpg?v=1739822179"},{"product_id":"probiotic-pro-bb536®-10-billion-active-cells","title":"Probiotic-Pro BB536® · 10 Billion Active Cells","description":"\u003cp\u003e- High potency: 10 billion CFU (colony forming units) of Bifidobacterium longum BB536 per capsule\u003cbr\u003e\n- Higher storage stability than other Bifidobacterium speciesBB536 is one of the most studied species in the world.\u003cbr\u003e\n- Resistance to gastrointestinal acidity allows the formula to reach the large intestine.\u003cbr\u003e\n- Stable at room temperature; refrigeration is not necessary\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nProbiotic-Pro BB536 is a very powerful probiotic containing 10 billion CFU per capsule of the Bifidobacterium longum BB536 species, one of the most studied in the world. It is a patented strain that has a remarkably longer and more stable shelf life than other probiotic supplements, and has a lower loss rate than other Bifidobacterium strains exposed to multiple different temperatures.\u003cbr\u003e\nIsolated from healthy human digestive tracts, Bifidobacterium has long been recognized as a beneficial genus, constituting more than 90% of total gastrointestinal bacteria in breastfed infants. It has been shown to have multiple immunomodulatory effects, such as increasing secretory IgA production and NK cell and neutrophil activity, as well as balancing Th1 and Th2 immune activity. It has also been shown to improve mucosal barrier function in the colon, in part by upregulating tight junction molecules. In clinical trials, BB536 supplementation has been shown to reduce allergic symptoms, decrease influenza infection, lower serum cholesterol levels, normalize elimination frequency, reduce pathogenic bacterial populations, and promote normalization of gastrointestinal tissues.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":41005600276565,"sku":"probiotic-pro-bb536-bioclinic-naturals-60c","price":33.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/viuav7r8sllyutswqicq.jpg?v=1739822179"},{"product_id":"ib-care™","title":"IB Care™","description":"\u003cp\u003e- Provides clinically effective amounts of peppermint, caraway and oregano oils in proven dosages.\u003cbr\u003e\n- Potent amounts of active components: 50% menthol (peppermint), 60% phenol (oregano) and 50% carvone (caraway).\u003cbr\u003e\n- Enteric coating improves effectiveness, allowing an antispasmodic effect in gastric and upper intestinal tissues.\u003cbr\u003e\n- Research confirms that peppermint oil is more effective and better tolerated when protected from stomach acid.\u003cbr\u003e\n- Enteric coating also reduces side effects and peppermint taste.\u003cbr\u003e\nIB Care contains enteric-coated peppermint, oregano, and caraway oils, which have been shown to have beneficial effects on various gastrointestinal disorders. Peppermint oil is known to influence gastric motility, accelerating early gastric emptying through an antispasmodic effect on the stomach. It also increases pyloric valve relaxation time, decreases lower esophageal sphincter resting pressure, and has benefits when combined with caraway oil, producing smooth muscle relaxation in the stomach and duodenum. Oregano oil has demonstrated antimicrobial effects against H. pylori, the primary cause of peptic ulcer disease and dyspepsia, as well as other gastrointestinal pathogens.\u003cbr\u003e\nClinically, enterally coated preparations of these oils have demonstrated their benefits in a number of clinical trials. A meta-analysis of twelve randomized trials involving a total of 835 patients with irritable bowel syndrome (IBS) compared the effects of peppermint oil to those of a placebo. Compared to the placebo group, patients taking peppermint oil had significant improvements in overall symptoms and abdominal pain. Controlled trials have shown improvement in dyspepsia and symptoms such as abdominal pain, heaviness, and pressure, regardless of H. pylori status, and even in patients with significant epigastric pain. Additionally, enteric-coated peppermint oil has demonstrated clinical effectiveness in a number of IBS trials, showing improvement in the majority of participants in both children and adults.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Softgels","offer_id":41085435543637,"sku":"80052526","price":16.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/lcu0kbimktpszkhjh2ts.jpg?v=1739822177"},{"product_id":"digest-progd-hp","title":"Digest-ProGD HP","description":"\u003cp\u003e- Provides fungal and bacterial proteases to hydrolyze difficult-to-digest proline-containing peptides, such as gluten and casein.\u003cbr\u003e\n- Provides a broad spectrum of carbohydrate digestion thanks to papain, bromelain and fungal digestive enzymes of plant origin.\u003cbr\u003e\n- Highly potent formulation allows for easy dosing, with nearly 300 mg of enzyme blend in each vegetarian capsule.\u003cbr\u003e\n- Perfectly suitable for vegetarians and vegans\u003cbr\u003e\nDigest-ProGD HP is a patented, high-potency enzyme blend for complete carbohydrate digestion. It contains fungal proteases derived from Aspergillus oryzae, bacterial proteases derived from Bacillus subtilis, plus comprehensive support for carbohydrate digestion with papain, bromelain, and fungal digestive enzymes. Aspergillus oryzae extracts are rich in prolyl endopeptidases and dipeptidyl peptidase IV (DPP-IV) – a multifunctional serine protease that targets proline-containing peptides, such as those found in gliadin and casein, two proteolysis-resistant proteins.\u003cbr\u003e\nIndeed, the protease activity of Aspergillus oryzae targets the proline-rich 33-mer of gliadin, perhaps the most immunotoxic peptide derived from gliadin. The proline-rich antigenic and immunomodulatory proteins found in gluten are thought to trigger an inflammatory response in patients with celiac disease or gluten sensitivity, often due to accidental exposure to gluten, even in people following a gluten-free diet. Aspergillus oryzae protease supplementation has also been associated with a bifidogenic effect in animals, suggesting a potential probiotic effect, as well as an increase in gut-protective amino acids.\u003cbr\u003e\nIn addition to fungal and bacterial proteases, Digest-ProGD HP provides alpha-amylase, cellulose and hemicellulose for comprehensive support of carbohydrate digestion.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":41005600440405,"sku":"80072201","price":31.99,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/nma2kydqhd4a4wrvz6q1.jpg?v=1739822176"},{"product_id":"dgl-400-mg","title":"DGL · 400 mg","description":"\u003cp\u003e- Provides DGL in the form of chewable tablets, the form associated with the greatest clinical effectiveness, because it allows the licorice to be released into the stomach and dispersed\/absorbed by the gastric mucosa.\u003cbr\u003e\n- Offers 400 mg of DGL per tablet, the clinically effective dose.\u003cbr\u003e\n- Deglycyrrhizination prevents adverse effects associated with licorice consumption.\u003cbr\u003e\n- Pleasant-tasting tablets for better compliance\u003cbr\u003e\n- Suitable for vegetarians\/vegans\u003cbr\u003e\nDeglycyrrhizinated licorice, or DGL, has been used clinically for decades, primarily for the treatment of peptic ulcers. Licorice contains numerous triterpenoids and hundreds of flavonoids that have been shown to inhibit several inflammatory enzymes, including cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). These enzymes decrease the production of several potent inflammatory compounds, including IL-6, prostaglandin E2, thromboxane B2, and leukotriene B4. It is important to note that this inhibition is not primarily due to glycyrrhizic acid, the component of licorice that was eliminated in DGL and is associated with mineralocorticoid excess and hypertension. Licorice contains numerous active compounds with anti-inflammatory, antimicrobial and anti-allergic actions, including glabridin and at least seven licochalcones. These compounds have been shown to prevent lipopolysaccharide (LPS)-induced production of inflammatory compounds, inhibit yeast and bacterial biofilm formation, and stimulate antioxidant enzymes.\u003cbr\u003e\nIn the clinic, DGL has been shown to be comparable in effectiveness to cimetidine in healing and preventing recurrence of ulcers. Furthermore, licorice extracts have been shown to inhibit the adhesion of H. pylori to the gastric mucosa, as well as the growth of antibiotic-resistant strains, suggesting multiple mechanisms of action for its anti-ulcer effect. The use of chewable tablets appears necessary for the effectiveness of DGL, as they allow distribution and absorption through the gastric mucosa.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"180 Tablets Croquables","offer_id":41085435510869,"sku":"80037407","price":23.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/ssp4ojnhgxkkippwlwu7.jpg?v=1739822176"},{"product_id":"coq10-400-mg","title":"CoQ10 · 400 mg","description":"\u003cp\u003e- Identical to the form produced by the human body for high bioavailability\u003cbr\u003e\n- Improves many health conditions, including cardiovascular disease, cellular breakdown and oxidative stress.\u003cbr\u003e\n- The higher dosage of 400 mg reduces the need to take multiple pills throughout the day and follows evolving research.\u003cbr\u003e\n- Free from contamination by unwanted residues or microorganisms, including bacteria or yeast\u003cbr\u003e\n- In a base of natural rice bran oil and vitamin E to guarantee a stabilized and highly absorbable form of CoQ10.\u003cbr\u003e\nThe majority of clinical uses of CoQ10 are based on its role as an antioxidant and its role in mitochondrial bioenergetics. It is a coenzyme for many reactions involved in cellular respiration, and it is necessary for the efficient formation of adenosine triphosphate (ATP), the cellular currency that fuels the majority of enzymatic reactions. It inhibits the peroxidation of cell membrane lipids as well as circulating lipoproteins.3,4 CoQ10 supports cardiac tissues by improving endothelial function and having a direct anti-atherogenic effect, which results in lowering blood pressure and improving ventricular contractility.\u003cbr\u003e\nHigh doses of CoQ10, up to 2400 mg per day, have been used primarily for neurodegenerative diseases such as Parkinson's disease and Huntington's disease, although high doses have also been used in patients with severe cardiovascular disease or advanced breast cancer. Clinical trials have shown benefits for a wide range of cardiovascular conditions, including congestive heart failure, hypertension and prevention of myocardial infarction. It has also shown clinical benefits for a number of other conditions, including migraine, periodontal disease, gingivitis, male infertility and statin-induced myopathy.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"30 Softgels","offer_id":41085435281493,"sku":"80028342","price":35.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/zc8tjegdkrial34bjabv.jpg?v=1739822168"},{"product_id":"nac-500mg","title":"NAC 500mg","description":"\u003cp\u003e- Supports the synthesis of glutathione, a key cellular antioxidant and conjugator of many environmental toxins\u003cbr\u003e\n- Improves endothelial function and supports nitric oxide synthesis500 mg of NAC per capsule allows for easy, therapeutic dosing levels\u003cbr\u003e\n- Stable and well-absorbed form of the easily oxidizable amino acid L-cysteine\u003cbr\u003e\nN-acetyl-L-cysteine ​​(NAC) is known for its various physiological and therapeutic benefits, attributed largely to its antioxidant, anti-inflammatory, and mucolytic effects. It is well known to increase glutathione, an essential intracellular antioxidant, by providing a stable form of L-cysteine, the limiting factor in glutathione synthesis. The number of conditions with impaired glutathione homeostasis continues to grow, including not only cardiovascular, neurodegenerative, pulmonary, and age-related diseases, but there is also increasing clinical recognition of metabolic disorders linked to exposure to environmental toxins, such as diabetes and persistent organic pollutants. By restoring glutathione levels, NAC is also well established as the most effective treatment. for acetaminophen toxicity.\u003cbr\u003e\nAdditionally, NAC's ability to cleave disulfide bonds gives it efficacy as a mucolytic agent, with clinical benefit for people with COPD and pulmonary fibrosis. Breaking disulfide bonds may also be the same mechanism by which it lowers homocysteine ​​and improves endothelial function in the coronary artery. disease. NAC has immunomodulatory and anti-inflammatory effects, improving flu symptoms and SLE activity. By modulating glutamatergic and neurotropic pathways, NAC has also been shown to benefit schizophrenia, bipolar disorder, and autism.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 capsules","offer_id":41005604864085,"sku":"NAC-bioclinic-naturals-90c","price":17.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/NAC-bioclinic-naturals.jpg?v=1739822166"},{"product_id":"glutathione-lipomicel","title":"Glutathione LipoMicel","description":"\u003cp\u003e- Provides the reduced form of glutathione, GSH\u003cbr\u003e\n- Glutathione is the main cellular antioxidant, protecting against many types of cell damage.\u003cbr\u003e\n- LipoMicel® technology creates a liquid micellar matrix that disperses glutathione into tiny microdroplets, resulting in a very stable delivery system for higher absorption than standard forms.\u003cbr\u003e\n- Clinically effective dose, 300 mg per capsule\u003cbr\u003e\nGlutathione is the most abundant intracellular antioxidant, not only providing protection against reactive oxygen and nitrogen species, but also playing a major role in multiple functions that maintain cellular homeostasis. Present in every cell, glutathione plays a role in immune function, gene expression, mitochondrial integrity, regulation of DNA and protein synthesis, and detoxification of endogenous and environmental toxins.\u003cbr\u003e\nWhile most intracellular glutathione is in a reduced state (GSH) with approximately 1% in the oxidized form (GSSG), this proportion can decrease in response to various cellular stressors, including heavy metals, high glucose concentrations, poor diet, heat shock. , reactive oxygen and nitrogen species, cigarette smoke and other toxins, including persistent organic pollutants. Indeed, it is the decline in GSH levels that has been linked to many chronic and age-related diseases, as well as the aging process itself. .\u003cbr\u003e\nGlutathione supplementation has been clearly shown to increase GSH levels at multiple sites in human clinical trials, including plasma, red blood cells, and lymphocytes. Additionally, improved delivery forms such as liposomal glutathione and polymeric micelles (liquid micelle matrix) improve bioavailability. , confer resistance to intestinal degradation and may also enhance intracellular glutathione delivery, bypassing potential enzymatic bottlenecks.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Softgels","offer_id":41085435084885,"sku":"glutathione-lipomicel-bioclinic-naturals-60gel","price":39.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/Glutathione-lipomicel-bioclinic-naturals-60gel.png?v=1739822165"},{"product_id":"emiq-activated-quercetin","title":"EMIQ Activated Quercetin","description":"\u003cp\u003e- Most absorbable form of quercetin\u003cbr\u003e\n- Provides 40 times greater absorption than regular quercetin\u003cbr\u003e\n- Provides 167 mg of enzymatically modified isoquercitrin (EMIQ), providing 50 mg of quercetin, as well as 50 mg of vitamin C per capsule\u003cbr\u003e\n- Provides anti-inflammatory, antioxidant, anti-allergic and cardiovascular benefits\u003cbr\u003e\n- Suitable for vegetarians and vegans\u003cbr\u003e\nQuercetin, a dietary flavonol known to be one of the most potent plant-derived antioxidants, has multiple biological actions, with preclinical studies showing anti-inflammatory, antithrombotic, and vasodilatory benefits. The limiting factor in the clinical effectiveness of quercetin appears to be its low bioavailability. Enzymatically modified isoquercitrin (EMIQ) is a mixture of quercetin monoglucoside and its alpha-oligoglucosides that has been shown to have significantly higher bioavailability than other available forms. In animals, EMIQ has been shown to produce a 40-fold increase in Cmax (peak plasma concentration) and an 18-fold increase in area under the curve compared to quercetin. In humans, EMIQ supplementation increased plasma concentrations to a significantly greater degree. than other forms, including aglycone and isoquercitrin (Q3G). Randomized placebo-controlled trials have shown that EMIQ has clinical benefits not seen with less absorbable forms. In a recent crossover trial in volunteers at risk for cardiovascular disease (i.e., with elevated blood pressure, lipids, glucose, or waist circumference), EMIQ improved endothelial function (as measured by flow-mediated vasodilation), a key risk factor for hypertension, atherosclerosis, and cardiovascular disease. American football players taking whey protein supplements experienced greater increases in lower extremity muscle mass and antioxidant protection when consuming 42 mg of EMIQ per day compared to whey alone. Two trials found that EMIQ reduced medication use and ocular symptoms. hay fever due to Japanese cedar pollinosis.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":41005604929621,"sku":"emiq-activated-quercetin-bioclinic-naturals-60c","price":25.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/EMIQ-activated-quercetin-Assured-naturals-60c.png?v=1739822165"},{"product_id":"omega-3-liquide","title":"Omega-3 Liquide","description":"\u003cp\u003e- Reduces inflammation\u003cbr\u003e\n- Repairs and reduces pathogenic bacteria in the intestine\u003cbr\u003e\n- Activation of lipolytic genes\u003cbr\u003e\n- Deactivation of lipogenic genes\u003cbr\u003e\n- Increases the use of fat as fuel\u003cbr\u003e\n- Improves brain functions\u003cbr\u003e\n- Maximizes strength gains following training\u003cbr\u003e\n- Decreases cortisol\u003cbr\u003e\nOmega 3 blend that helps contribute to cognitive health and brain function. Helps maintain cardiovascular health, reduce blood triglyceride levels and promote healthy mood balance in adults.\u003c\/p\u003e","brand":"NIH Suppléments","offers":[{"title":"250 ml","offer_id":41005606731861,"sku":"omega-3-liquid-nih-250ml","price":49.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/LIQUIDEPADHA250ML_1.webp?v=1739822162"},{"product_id":"gut-restore","title":"Gut Restore 2.0","description":"\u003cp\u003e- Clinically studied to reduce symptoms associated with IBS (irritable bowel syndrome) and inflammatory bowel disease.\u003cbr\u003e\nPromotes the assimilation of food.\u003cbr\u003e\nGreatly improves intestinal immune defenses.\u003cbr\u003e\nPromotes intestinal flora (prebiotic).\u003cbr\u003e\nReduces inflammation.\u003cbr\u003e\nHelps reduce histamine production\u003cbr\u003e\nTraditionally used in herbal medicine to relieve benign inflammation of the gastrointestinal mucosa, e.g. during gastritis, gastric or duodenal ulcer or enteritis.\u003c\/p\u003e","brand":"NIH Suppléments","offers":[{"title":"380g","offer_id":41005607125077,"sku":"gut-restore-supplement-sante-intestinale-nih-supplements-380g","price":59.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/gut-restore-2-nih-supplements-energieplp-unytii-supplements.webp?v=1739822153"},{"product_id":"aor34236","title":"Pro Thyroid","description":"\u003cp\u003eSupports the function of the thyroid gland.\u003cbr\u003e\n- Supports an underactive thyroid\u003cbr\u003e\n- Effective fatigue and adrenal support\u003cbr\u003e\n- Supports healthy weight management\u003cbr\u003e\n- Vegetarian formula with nutrients and botanical extracts\u003cbr\u003e\nPro Thyroid helps with both the production of thyroid hormones and the conversion of inactive T4 hormones into active T3 hormones. It contains nutrients and herbs that help prevent and reverse thyroid insufficiency, including tyrosine, iodine, and the botanical herbs Coleus forskohlii and Bacopa monnieri. Tyrosine and iodine are the building blocks of the thyroid hormones T3 and T4. Zinc helps support the conversion of T4 to T3, while selenium may help decrease anti-TPO antibodies in people with Hashimoto's disease.\u003cbr\u003e\nAOR Advantage\u003cbr\u003e\nPro Thyroid contains all the nutrients necessary for optimal thyroid function as well as Ayurvedic herbs to enhance its activity.\u003c\/p\u003e","brand":"AOR PRO","offers":[{"title":"90 Capsules","offer_id":41005608009813,"sku":"pro-thyroid-aor-90-capsules","price":50.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/AOR-34236-Pro-Thyroid-250cc-Wrapround-Render-Front-CAN-NV01.00.png?v=1739822146"},{"product_id":"fertility-matrix-ovulatory-oocyte-support","title":"Cycle Matrix (Fertility Matrix) Ovulatory \u0026 Oocyte Support","description":"\u003cp\u003e- A powdered blend of evidence-based nutrients for optimal hormonal regulation, egg development and fertility support in women. Peach and mango flavor for improved compliance Designed to support female fertility, including ovulation, oocyte quality, embryonic development and successful gestation. Inositol and NAC support insulin and hormonal balance in polycystic ovary syndrome (PCOS), a condition known to predispose to infertility. Coenzyme Q10 and PQQ provide mitochondrial support to improve egg quality, embryo implantation and embryonic growth. L-arginine increases blood flow to the pelvic organs and promotes endometrial thickness, endometrial receptivity and follicular growth. Folate is provided in the active form of 5-MTHF to improve oocyte development, embryo quality and live birth rate, as well as choline to support the development of the fetal nervous system. Vitex agnus-castus contains diterpene compounds and flavonoids that exert dopaminergic action, reduce prolactin levels and increase endogenous progesterone. Each 276-gram bottle contains a 30-day supply in a peach and mango flavored powder for better compliance and ease of use. Vegan and free of GMOs, gluten, soy and dairy.\u003cbr\u003e\nInfertility is a growing health problem for Canadians, with up to 1 in 6 couples currently experiencing difficulty conceiving. Of course, infertility can occur as a result of male or female health problems, or a combination of problems with both partners. Although there can be several underlying causes or complicating factors, in women the cause is often related to egg production, egg quality, menstrual irregularities, or hormonal imbalances. Cycle Matrix - Ovulatory \u0026amp; Oocyte Support - from Cyto-Matrix combines a selection of natural health ingredients to target and improve these parameters in women suffering from infertility.\u003cbr\u003e\nA clinical picture that often leads to infertility in women is polycystic ovary syndrome (PCOS). Physiologically, women with PCOS exhibit insulin resistance and subsequent elevations in androgens and suboptimal progesterone during the luteal phase of the menstrual cycle. This often results in irregular periods, lack of egg maturation, anovulation and infertility. Fortunately, dietary modifications, lifestyle changes, and a number of nutritional supplements have been shown to improve this dysfunctional pattern. Inositol is a great example of a well-studied nutrient to benefit PCOS.\u003cbr\u003e\nInositol is a natural isomer of glucose and an important nutrient in the B vitamin family. It is a key component of the cell membrane and increases the sensitivity of cellular receptors to serotonin, acetylcholine, norepinephrine, thyroid hormones and insulin. At doses of 1-4 grams\/day, inositol has been shown to improve insulin and glucose control, regulate ovulation, improve egg quality, reduce androgens, and improve fertility in women with PCOS. When combined with folic acid, inositol has been shown to improve in vitro fertilization (IVF) rates. Additionally, one study found that this same combination of nutrients was more effective at inducing ovulation and achieving pregnancy in infertile women with PCOS when directly compared to metformin.\u003cbr\u003e\nWhen it comes to folate, although it is classically known for its importance during the first trimester of pregnancy in preventing neural tube defects like spina bifida and anencephaly, research has shown that it also plays a crucial role in fertility and pregnancy preparation. For example, studies have shown that higher folate levels are associated with improved oocyte development, embryo quality and implantation, clinical pregnancies, and live birth rates. Additionally, research has shown that lower folate levels may be accompanied by a higher risk of early miscarriage. The high prevalence of genetic changes in the 5-MTHFR gene strongly suggests that 5-methyltetrahydrofolate (5-MTHF), as opposed to synthetic folic acid, is the necessary form of supplementation in all women to ensure proper absorption and utilization.\u003cbr\u003e\nN-acetylcysteine ​​(NAC) is another promising treatment for PCOS and infertility. NAC is the rate-limiting substrate necessary for the production of endogenous glutathione, one of the most powerful antioxidant and detoxifying compounds in our body. NAC has been widely used in clinical trials to support optimal health, particularly in liver protection and respiratory disorders. In the context of women's health, NAC has been shown to improve insulin sensitivity, restore ovulation, and improve egg quality in PCOS, while significantly increasing the live birth rate in women with unexplained recurrent pregnancy loss. Finally, NAC has been shown to improve pregnancy rates when used as an adjunct to clomiphene citrate in intrauterine insemination (IUI) cycles in women with unexplained infertility. Mitochondrial dysfunction, resulting from a number of environmental toxins, disease states, or aging, is another identified mechanism behind female infertility. This may explain why coenzyme Q10 (CoQ10), a nutrient known to support mitochondrial function and increase ATP energy production, has shown so much promise in various cases of female infertility. Although CoQ10 has been classically used as a cardiovascular nutrient, recent research has shown that CoQ10 improves conception rates by promoting egg quality, embryo implantation, and embryonic growth. Pyrroloquinoline quinone (PQQ) is a unique antioxidant that has synergistic beneficial effects on mitochondrial function when used with CoQ10.\u003cbr\u003e\nIn some cases of infertility, the health of the endometrial lining may be a contributing concern and L-arginine may be helpful. Larginine has been supplemented primarily for its ability to upregulate nitric oxide and improve blood flow, explaining its benefits on intermittent claudication and physical performance, but it has also been shown to benefit women's health. Increased nitric oxide promotes blood flow to the pelvic organs, supporting endometrial receptivity, endometrial thickness, and follicular growth. One particular study found that L-arginine improved endometrial thickness and pregnancy rates in women with thin endometrial linings.\u003cbr\u003e\nFinally, some cases of infertility may be linked to low progesterone levels, independent of PCOS. Vitex agnus-castus, commonly known as Chastetree, has long been used to increase progesterone levels and address women's health concerns. The diterpene compounds and flavonoids present in vitex have been shown to exhibit dopaminergic action, thereby reducing prolactin levels and increasing endogenous progesterone. Collectively, these actions would explain why clinical research has shown that vitex can improve menstrual cycle regularity and PMS symptoms. In theory, better hormonal balance can have positive effects on female infertility.\u003cbr\u003e\nCycle Matrix - Ovulatory and Oocyte Support combines all of these evidence-based nutrients to support women's fertility, including ovulation, oocyte quality, embryonic development and successful gestation. Additionally, additional choline to positively influence the formation of the fetal brain and spinal cord. Fertility Matrix - Ovulatory and Oocyte Support comes in a convenient peach and mango flavored powder for improved compliance and ease of use. Each 276 gram bottle contains a 30 day supply. Fertility Matrix - Ovulatory and Oocyte Support is vegan and free of GMOs, gluten, soy and dairy.\u003c\/p\u003e","brand":"Cyto-Matrix","offers":[{"title":"276 g","offer_id":41005627801685,"sku":"fertility-matrix-ovulatory-oocyte-support-cyto-matrix-276g","price":98.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/cycle_matrix_cyto-matrix_energieplp_unytii_supplements.png?v=1739822123"},{"product_id":"fibre-x","title":"Fiber-X","description":"\u003cp\u003e- Fiber formula - Digestive Health\u003cbr\u003e\nPromotes the regeneration of the intestinal membrane.\u003cbr\u003e\nAllows increased assimilation of nutrients.\u003cbr\u003e\nEach capsule contains 650 mg of selected, very high quality psyllium husks.\u003c\/p\u003e","brand":"XPN","offers":[{"title":"180 capsules","offer_id":41005641531477,"sku":"fiber-x-xpn-180-capsules","price":21.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/Fiber-X-_XPN_EnergiePLP_Unytii_Supplements.webp?v=1739822087"},{"product_id":"anabol-x","title":"Anabol-X","description":"\u003cp\u003e- Helps optimize testosterone\u003cbr\u003e\n- Also promotes better stress management\u003cbr\u003e\n- Health of the hormonal system\u003cbr\u003e\n- Allows a better balance of neurotransmitters (dopamine and serotonin)\u003cbr\u003e\nNatural testosterone optimization. The modern lifestyle is very hard on men and their testosterone: lack of sleep and managing the various stressors of life has its share of consequences: low testosterone is one of them.\u003cbr\u003e\nTestosterone is synonymous with masculinity and muscle mass, but also with recovery and performance: better testosterone levels will greatly help with recovery and motivation.\u003cbr\u003e\nWe opted for a blend of zinc and resveratrol which are known to play a role in controlling aromatization and optimizing testosterone. In addition, zinc is necessary for the production of testosterone and resveratrol is one of the most interesting compounds for human health.\u003cbr\u003e\nWhen it comes to stress management, we have opted for adaptogenic plants. Among adaptogenic plants, there are several that can help you optimize your hormones, but eurycoma longifolia is really the best choice for increasing free (and therefore usable) testosterone, and also promotes better stress management.\u003cbr\u003e\nMaca, for its part, plays an important role in the health of the hormonal system. Tyrosine and B6 complete the mixture and allow a better balance of neurotransmitters (such as dopamine and serotonin).\u003c\/p\u003e","brand":"XPN","offers":[{"title":"90 capsules","offer_id":41005642907733,"sku":"anabol-x-xpn-400g","price":44.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/Anabol-X-90caps_XPN_EnergiePLP_Unytii_Supplements.webp?v=1739822076"},{"product_id":"liposomal-gaba-l-theanine","title":"Liposomal GABA \u0026 L-Theanine","description":"\u003cp\u003e- GABA is an inhibitory neurotransmitter in the brain, responsible for calming the overactive central nervous system, and has been studied for its ability to improve mood, sleep parameters, and subjective and objective markers of the stress response.\u003cbr\u003e\n- L-Theanine is an amino acid naturally found in green tea that can balance neurotransmitters in the brain and promote a calm but focused state.\u003cbr\u003e\n- Patented Cyto-Sorb technology uses a two-phase emulsion process with phosphatidylcholine from non-GMO sunflower, vitamin E and organic coconut vegetable glycerin to create micellar liposomes and significantly improve bioavailability, stability and sustained release\u003cbr\u003e\n- Each teaspoon provides 300 mg of micellar liposomal GABA and 100 mg of micellar liposomal L-theanine in a delicious natural orange flavor for improved compliance.\u003cbr\u003e\n- 225 ml per bottle provides 45 servings\u003cbr\u003e\nStress, insomnia, and mood disorders often present clinically together and share common pathophysiological pathways. Although hormonal intake, genetic predispositions, and biochemical individualities may vary, an overactive nervous system is a common clinical concern and target for treatment. Cyto-Matrix Liposomal GABA + L-Theanine is designed to deliver two evidence-based nutrients in a unique, enhanced delivery system to optimally calm the nervous system.\u003cbr\u003e\nGamma-aminobutyric acid, more commonly known as GABA, is the primary inhibitory neurotransmitter found in the human brain and is responsible for calming the mind during excitatory conditions. Lower brain levels of GABA have been correlated with various mood disorders, sleep problems, and other neurological disorders. Studies indicate that GABA can improve relaxation and concentration during times of stress, reduce sleep latency, and increase the time spent in deep sleep. Additionally, if pre-supplemented with GABA, individuals exhibit stable levels of salivary immunoglobulin A (IgA) and reduced levels of cortisol when exposed to stress. Collectively, these mechanisms all indicate a reduced and more balanced stress response.\u003cbr\u003e\nL-theanine is another compound well known for calming the mind and improving focus, in part through activation of GABA receptors. As an amino acid found naturally in green tea, research has shown that L-theanine can positively impact serotonin, dopamine, and GABA in the brain. This ultimately leads to an increase in alpha brain waves and a calm, yet focused state. Clinical trials have confirmed that these actions lead to reduced stress, improved learning ability and improved mood. L-Theanine also has potential cardiovascular and detoxification benefits through protection against cholesterol and increasing glutathione levels. Collectively, L-Theanine balances the nervous system and provides powerful antioxidant support to protect the body from damage.\u003cbr\u003e\nCyto-Matrix Liposomal GABA + L-Theanine has combined these two effective, evidence-based nutrients in a delivery system optimized for better clinical outcomes. Liposomal delivery systems were originally developed to optimize the pharmacokinetics and efficacy of pharmaceutical drugs. These same principles have now been applied to natural health ingredients. A liposome consists of a single-layer or multilayer phospholipid structure with an aqueous core. The active ingredients can be placed inside the aqueous core or in the phospholipid bilayer, where they are protected from various enzymatic and digestive processes.\u003cbr\u003e\nUltimately, liposomes improve the bioavailability of active ingredients.\u003cbr\u003e\nHowever, not all liposomal delivery systems are created equal. Liposomes are several hundred nanometers in size, meaning there is still a significant amount of digestion that must occur to reduce the surface area and allow for proper absorption. Micelles, on the other hand, are significantly smaller and can be absorbed directly at a size of around 20 nanometers.\u003cbr\u003e\nCyto-Matrix Liposomal GABA + L-Theanine uses Cyto-Sorb, a unique and patented technology, to create a stable, multi-layered liposome with additional micellar delivery of nutrients. These methods provide micronutrient stability and improved bioavailability, while also promoting delivery of active ingredients to intestinal sites of absorption in a sustained-release manner.\u003cbr\u003e\nCyto-Sorb liposomal formulas are produced by a two-phase emulsion process using phosphatidylcholine from non-GMO sunflower, vitamin E and organic coconut vegetable glycerin. Potassium bicarbonate is strategically added to stabilize the active ingredient, prevent oxidation and improve flavor. Cyto-Matrix Liposomal GABA + LTheanine provides 300 mg of GABA and 100 mg of L-theanine per teaspoon in micellar liposomal delivery for improved bioavailability and clinical effectiveness. Each bottle provides 45 servings in a delicious natural orange flavor.\u003c\/p\u003e","brand":"Cyto-Matrix","offers":[{"title":"225ml","offer_id":41005656571989,"sku":"liposomal-gaba-l-theanine-225ml","price":49.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/image_08ab1f1d-874a-427e-b7e8-772ed503e531.png?v=1739822053"},{"product_id":"mag-matrix-liquid-lemon","title":"Mag Matrix - Liquide - Citron","description":"\u003cp\u003e- Provides magnesium in a therapeutic blend of glycinate, citrate and malate for a well-absorbed and well-tolerated supply of magnesium\u003cbr\u003e\n- Liquid form for variable and convenient dosing, providing 210 mg of elemental magnesium per tablespoon\u003cbr\u003e\n- Naturally lemon flavored with xylitol and stevia\u003cbr\u003e\nMagnesium is one of the most important minerals for our health. It is necessary for maintaining the proper functioning of nerves and muscles through its regulation of calcium, the creation of cellular energy in mitochondria and also acts as a cofactor to build DNA, RNA and many proteins. Despite its great importance, it is commonly deficient in the Canadian population due to poor diet, medication exhaustion, and stress. Suboptimal magnesium levels create a pro-inflammatory state in the body with many health implications.\u003cbr\u003e\nAs more research continues to develop regarding the benefits of magnesium for human health, it is hard not to consider additional supplementation in most patients. Clinical trials and large-scale evidence have shown that magnesium may be helpful for muscle tension, fatigue, anxiety, depression, insomnia, attention deficit hyperactivity disorder (ADHD), cardiovascular disease, dementia, osteoporosis, migraines, and more.\u003cbr\u003e\nMagnesium bis-glycinate is a form of magnesium that combines one molecule of the essential mineral with 2 molecules of the inhibitory amino acid glycine. This chelated bond is advantageous because it remains stable throughout the digestive tract, it prevents magnesium from binding to other compounds, and it provides access to dipeptide transport sites. Ultimately, this leads to greater absorption and tolerance in the body.\u003cbr\u003e\nMagnesium malate is another highly bioavailable form of magnesium. Malate, also known as malic acid, is actually a substrate found in mitochondria that is used to create ATP and it works synergistically with magnesium to improve energy and reduce pain. In fact, placebo-controlled and open-label trials have confirmed that magnesium malate can reduce pain and tenderness in people with fibromyalgia.\u003cbr\u003e\nMag-Matrix Liquid provides 210 mg of elemental magnesium per tablespoon in a bioavailable blend of glycinate, malate and citrate. This magnesium blend is in liquid form for convenient dosing and is naturally lemon flavored for better patient compliance.\u003c\/p\u003e","brand":"Cyto-Matrix","offers":[{"title":"450ml","offer_id":41005665288277,"sku":"mag-matrix-liquid-lemon-450ml","price":49.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/image_f5fe05dd-ebb5-4956-8158-ce55e60bc286.png?v=1739822021"},{"product_id":"k2-d3-matrix-liquid","title":"K2 D3 Matrix - Liquid","description":"\u003cp\u003e- K2 and D3 provided in combination for optimal cardiovascular and bone health\u003cbr\u003e\n- Vitamin K2 is found under the name K2Vital, the patented MK-7 not derived from soy\u003cbr\u003e\n- In a medium chain triglyceride oil base to promote optimal absorption and bioavailability\u003cbr\u003e\nK2-D3 Matrix Liquid is designed for optimal delivery of vitamins K2 and D3 into the body. Together, these vitamins work synergistically to support heart health, bone health, immune function and more.\u003cbr\u003e\nVitamin K2 is a nutrient that is now well known to be crucial for the proper distribution of calcium in the skeletal system and the prevention of arterial calcification in the cardiovascular system. It does this through its ability to activate two proteins, osteocalcin and matrix-GLA.\u003cbr\u003e\nVitamin D3, also known as cholecalciferol, is the preferred form of vitamin D for optimal bioavailability and function in the body. Classically, vitamin D3 is known for its ability to positively regulate the absorption of calcium from the intestine. However, research has found that it is imperative for countless actions in the body and is necessary for healthy immune function, mood health, cardiovascular function, skin health, and proper gene expression. In fact, many experts now refer to vitamin D3 as a hormone because of these many actions and its ability to actually change genes in the body.\u003cbr\u003e\nEach dose (4 drops) of K2-D3 Matrix Liquid from Cyto-Matrix contains 120 mcg of vitamin K2 in its most active MK-7 form, as well as 1000 IU of vitamin D3. Vitamin K2 is found under the name K2Vital®, the patented MK-7 not derived from soy. K2-D3 is in a medium chain triglyceride oil base to promote optimal absorption and bioavailability.\u003c\/p\u003e","brand":"Cyto-Matrix","offers":[{"title":"15ml","offer_id":41005665943637,"sku":"k2-d3-matrix-liquid-15ml","price":29.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/image_60bb033f-2bdd-436c-8a44-05d4a30b3474.png?v=1739822015"},{"product_id":"dt-matrix","title":"DT Matrix","description":"\u003cp\u003e- Contains a blend of 7 herbs to support healthy liver and kidney function and improve the body's ability to detoxify.\u003cbr\u003e\n- Silybum marianum, cynara scolymus and picrorhiza kurroam have been shown to protect the liver and improve gallbladder function\u003cbr\u003e\n- Silybum marianum is standardized to 80% silymarin and picrorhiza kurroam is standardized to 4% kutkins for greater potency and improved effectiveness.\u003cbr\u003e\n- Urticaria dioica, arctostaphylos uva-ursi and arctium lappa are included for their diuretic properties and to promote healthy renal clearance\u003cbr\u003e\n- Beta vulgaris is also added to the formula to upregulate nitric oxide production and improve blood circulation in the body.\u003cbr\u003e\nThe human body is regularly taxed with pollutants, pesticides, allergens and other exogenous toxins. Although our detoxification systems are adept at working together to ensure that these compounds are excreted from the body as quickly as possible, they can often be overwhelmed and need support. Although eliminating exposure to toxins is integral to overall success, optimal liver and kidney function must be supported. Fortunately, various plant extracts have been shown to positively regulate the function of these crucial detoxification organs.\u003cbr\u003e\nSilybum marianum is undoubtedly the best-known liver-protecting herb. Human clinical trials have shown that milk thistle extract can normalize liver enzymes in infectious hepatitis or toxin damage and increase endogenous glutathione production. SIlybum marianum has also been shown to improve fasting blood sugar, insulin levels, HbA1c and body mass index (BMI) in people with diabetes and may help reduce inflammation in the lining of the digestive tract.\u003cbr\u003e\nLesser-known hepatoprotective herbs include Cynara scolymus and Picrorhiza kurroam. Cynara scolymus is able to increase bile secretions and reduce bloating, abdominal pain, flatulence and nausea in people suffering from dyspepsia and IBS. Research also supports its ability to lower triglycerides, reduce LDL cholesterol, and improve liver enzymes in people with nonalcoholic steatohepatitis (NASH). Picrorhiza kurroam, on the other hand, has antiviral properties. A randomized, double-blind, placebo-controlled trial in patients with acute viral hepatitis showed that two weeks of supplementation resulted in a significant decrease in bilirubin, SGOT, and SGPT values ​​compared to placebo.\u003cbr\u003e\nWhen it comes to promoting healthy renal clearance, Urticaria dioica, arctostaphylos uva-ursi, and Arctium lappa are all effective diuretics, but each herb also has unique complementary actions. For example, dioic urticaria can improve urinary tract symptoms in men with benign prostatic hyperplasia (BPH) and also decrease fasting blood sugar and HbA1c in type 2 diabetics. Arctostaphylos uva-ursi exerts astringent, softening and antiseptic effects on the urinary tract membranes and, therefore, also protects against urinary tract infections. Finally, Arctium lappa has been shown to decrease elevated transaminase and restore glutathione levels in animal livers.\u003cbr\u003e\nCollectively, these herbs are standardized to active ingredients, where applicable, and included in Cyto-Matrix's DT-Matrix to support both healthy liver and kidney detoxification. Beta vulgaris is also added to the formula to upregulate nitric oxide production and improve blood flow in the body, another important step in optimal detoxification pathways. DT-Matrix is ​​indicated to support optimal liver and kidney function or for symptoms of excessive toxic burden such as lack of energy, headaches, malaise, constipation, and poor cognition.\u003c\/p\u003e","brand":"Cyto-Matrix","offers":[{"title":"90 Capsules","offer_id":41005667221589,"sku":"dt-matrix-90-capsules","price":43.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/image_1b421ea7-75a9-4ff1-beb1-e6d96660d92e.png?v=1739822003"},{"product_id":"cyto-fibre-powder","title":"Cyto Fibre - Poudre","description":"\u003cp\u003e- Very tolerable with minimal flatulence, bloating and abdominal cramps according to digestive tolerance studies\u003cbr\u003e\n- Shown to increase the number of beneficial bacteria, encourage the production of short-chain fatty acids, improve inflammatory cytokine profiles and support intestinal permeability\u003cbr\u003e\n- Certified organic, non-GMO and FODMAP-free\u003cbr\u003e\nPrebiotic fiber shapes the health of our microbiota and is essential for promoting many healthy digestive processes, including bowel movement regularity, stool volume and transit time. However, the implications of fiber intake extend far beyond the digestive tract. Increased fiber intake helps improve satiety, support healthy cholesterol levels, and regulate blood sugar levels. Unfortunately, the vast majority of the Canadian population lacks dietary fiber, meaning supplementation can play a valuable role.\u003cbr\u003e\nUnlike the significant benefit of increased fiber intake, some additional fiber may be poorly tolerated and cause many digestive problems. For example, high doses of fructo-oligosaccharides (FOS) or psyllium fiber can cause bloating, bloating, flatulence, and abdominal cramping when fermented by the gut microbiota. This leads many patients and practitioners to avoid their use altogether. However, there are better options because not all prebiotic fibers cause digestive discomfort.\u003cbr\u003e\nFibregum is an example of an extremely well-tolerated prebiotic fiber that causes minimal gas and bloating when supplemented, even in high doses up to 30 grams per day. Fibregum has been widely studied and shown to increase the growth of various lactobacilli, bifidobacteria, and the anti-inflammatory microbe Faecalibacterium prausnitzii. Additionally, Fibregum has been shown to significantly increase the production of short-chain fatty acids (SCFA, including butyrate), positively influence pro- and anti-inflammatory cytokine profiles in the colon, and support healthy intestinal permeability. Unlike FOS which is rapidly fermented in the ascending colon, Fibregum is slowly and gradually fermented in the ascending, transverse and descending colon, leading to better clinical results and tolerability.\u003cbr\u003e\nCyto-Fibre is an all-natural, certified organic, non-GMO, and non-FODMAP source of prebiotic fiber to support digestive tract health. Made from acacia gum, Fibregum is flavorless and dissolves easily. This means that Cyto-Fibre can be easily integrated into your patients' treatment protocols with high compliance, effectiveness and tolerability.\u003c\/p\u003e","brand":"Cyto-Matrix","offers":[{"title":"325g","offer_id":41005667647573,"sku":"cyto-fibre-powder-325g","price":38.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0568\/6316\/2453\/files\/image_6d4161e9-bbd2-486d-956f-6a99dc4ea6af.png?v=1739821996"}],"url":"https:\/\/supplements.cavemanstrong.com\/collections\/collection-favorites-products.oembed?page=5","provider":"Caveman Strong - Josee Filion","version":"1.0","type":"link"}