- Liquid iron delivered in a polysaccharide-iron complex (PIC), an extremely well tolerated, safe and highly bioavailable form
- Indicated for people suffering from iron deficiency anemia, low ferritin levels and associated symptoms of fatigue, hair loss, cognitive impairment, low mood, weakened immunity and hormonal imbalances
Iron continues to be the most common nutrient deficiency in the developed world, with particularly high prevalence among women and during pregnancy. In fact, 1 in 2 women will be iron deficient at some point in their lives and even more will suffer from symptoms associated with suboptimal iron levels. Although fatigue, weakness, hair loss and paleness are classic symptoms of iron deficiency anemia, low iron levels affect many other body systems.
For example, iron deficiency has been found to be a common cause of agitated syndrome in approximately 1 in 4 cases and an iron supplement may improve symptoms. This is thought to be achieved by iron's upregulation of dopamine synthesis from tyrosine. It is also well documented that children and adults perform worse on tests of mental function in iron deficiency states, with areas such as attention, memory and concentration affected.
Iron also plays an essential role in many hormonal pathways. Iron is required for thyroid conversion of thyroxine (T4) to triiodothyronine (T3) and, in hypothyroidism with concomitant iron deficiency, combined treatment with iron and levothyroxine has been shown to be superior to either treatment alone. In women with heavy menstrual bleeding, iron deficiency can cause a recurrent condition of heavy menstrual bleeding by weakening the uterine muscles, thus worsening the condition. Evidence also shows that women with unexplained infertility and suboptimal iron status may benefit from iron restoration therapy.
Finally, iron is necessary for proper immune function through the production of cytokines in macrophages and a state of iron deficiency can lead to an insufficient immune response. For example, research on people with oral candidiasis has shown that iron restoration can reduce the number of salivary candidiasis and reduce oral lesions.
Despite all the health benefits of targeted iron supplementation, many women and individuals with iron deficiency are hesitant to take iron supplements or become noncompliant due to digestive side effects such as constipation, nausea, and upset stomach.
Bio-Ferra from Cyto-Matrix is a highly bioavailable liquid iron supplement containing a polysaccharide iron complex (PIC). PIC is unique in that it is non-ionic, does not require vitamin C for absorption, and is extremely safe with an LD50 (lethal dose 50) of 5,000 mg/kg, compared to the toxicity potential of iron salts with an LD50 of only 230mg/kg. Each teaspoon of Bio-Ferra provides 20 mg of elemental iron flavored with natural green apple and is suitable for vegans and vegetarians.
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