- Designed to relieve a variety of muscle cramps and spasms, including premenstrual cramps, musculoskeletal pain and digestive disorders
- Viburnum opulus and Scutellaria lateriflora are both traditionally known for their powerful antispasmodic abilities
- Zingiber officinale, Cinnamon aromaticum and Foeniculum vulgare have all been studied for their ability to improve premenstrual cramps and other menstrual symptoms
- Zingiber officinale is standardized to 20% gingerol, a powerful active ingredient known to inhibit inflammation
- Magnesium comes as an amino acid chelate for optimal stability and absorption to relax muscles and nerve tissues
- Vitamin B6, in its active form pyridoxal-5-phosphate, improves the production of serotonin and GABA in order to modulate the perception of pain
Both acute pain and chronic pain involve a number of interacting physiological mechanisms involving the nervous system, musculoskeletal system, and immune system. While the most targeted pathways involve inflammation and pain receptors, smooth and skeletal muscle spasms are often involved. Clinically, there are a number of herbal preparations that can target these cramps and reduce the pain.
For example, Viburnum opulus, more commonly known as cramp bark, is an herb traditionally used to relieve all kinds of cramps, including abdominal muscle spasms and spasms associated with menstruation. Scutellaria lateriflora, commonly known as skullcap, is another herb traditionally used for its antispasmodic actions, but there are many other proven herbal remedies that have shown promise in relieving cramps and spasms. Ginger is a great example.
Many people associate ginger with its anti-nausea abilities, but it has actually been widely studied in the treatment of dysmenorrhea. Several trials confirm that ginger can effectively reduce menstrual pain when taken during the first 3-4 days of the menstrual cycle. In fact, ginger has been shown to be as effective as various anti-inflammatory medications such as ibuprofen or as a promising adjunct therapy to NSAID medications. Additionally, research trials have shown that ginger can decrease exercise-induced muscle soreness, improve recovery after exercise, reduce migraine severity and duration, and reduce joint pain in people with osteoarthritis.
Cassia cinnamon is another herb that has been studied for its ability to improve symptoms of dysmenorrhea. Several studies have shown that cassia cinnamon is able to reduce the severity of menstrual pain and associated nausea and vomiting, while also reducing the amount of menstrual bleeding. Similar to ginger, cinnamon has been studied alongside NSAID medications and found to be equally effective with an impressive safety profile.
Finally, Foeniculum vulgare, also known as sweet fennel, is not only an effective remedy for digestive problems such as constipation and irritable bowel syndrome. Indeed, fennel's antispasmodic abilities provide these benefits, but it also has analgesic and anti-inflammatory properties that may collectively help explain its effectiveness in clinical trials for reducing pain in dysmenorrhea.
Cramp Matrix combines traditional antispasmodic herbal extracts such as Viburnum opulus and Scutellaria lateriflora with evidence-based herbs such as Zingiber officinale, Cinnamomum aromaticum and Foeniculum vulgare in high potency extracts and standardizations. Additional nutrients such as magnesium and vitamin B6 complement the formula for muscle relaxation and neurotransmitter regulation to modulate pain perception, respectively. Magnesium comes as an amino acid chelate for optimal stability and absorption, while vitamin B6 is included in its active form of pyridoxal-5-phosphate.
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