- Indicated to regulate mood, promote sleep, improve symptoms of fibromyalgia and help with weight management
- 100 mg of 5-HTP as a therapeutic amino acid to support the production of serotonin and melatonin
- 100mg of L-glycine encourages healthy cell signaling in the nervous system to balance mood and improve sleep
- 10 mg pyridoxal-5-phosphate (P-5-P), the biologically active form of vitamin B6, added for the efficient conversion of 5-HTP to serotonin and the production of other neurotransmitters
The human brain is a complex structure that relies on several chemicals to communicate information. For example, the neurotransmitter serotonin plays an important role in mental health, temperature regulation, and pain sensation, while the hormone melatonin is needed to regulate circadian rhythm. As one might imagine, any nutrients that can support these brain chemicals have vast therapeutic potential. 5-Hydroxytryptophan (5-HTP) is one such nutrient, as it is the direct precursor to serotonin and, subsequently, melatonin.
5-HTP is particularly used to promote healthy mood balance. Yet its ability to upregulate serotonin offers application in many other conditions with mental and psychological components. Numerous research trials have shown that 5-HTP may also improve sleep difficulties, binge eating, weight management, headaches, and fibromyalgia.
The conversion of 5-HTP to serotonin requires vitamin B-6 as a cofactor, just as the synthesis of GABA and dopamine also requires vitamin B6. This is thought to explain why vitamin B-6 as a standalone treatment has been shown to be beneficial in treating premenstrual symptoms, premenstrual dysphoric disorder, and pregnancy-induced nausea. Pyridoxal-5-phosphate (P-5-P) is the coenzyme form of vitamin B6 that is biologically active. Unlike pyridoxine HCl, P-5-P is immediately ready for use in the nervous system after absorption from the digestive tract.
Glycine acts as another important cellular signal in the brain. Glycine's role in the nervous system is evident through multiple clinical trials examining the benefits of sleep and obsessive-compulsive among other mental disorders. For example, ingesting glycine an hour before sleep has been found to improve sleep latency and quality, reduce morning fatigue, and improve cognitive performance the next day.
Cyto-Calm provides a therapeutic combination of 5-HTP, biologically active vitamin B6 and glycine. Collectively, these nutrients work to support and balance the brain's neurotransmitters and work synergistically to improve mood and sleep.
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