Digest-ProGD HP

- Provides fungal and bacterial proteases to hydrolyze difficult-to-digest proline-containing peptides, such as gluten and casein.
- Provides a broad spectrum of carbohydrate digestion thanks to papain, bromelain and fungal digestive enzymes of plant origin.
- Highly potent formulation allows for easy dosing, with nearly 300 mg of enzyme blend in each vegetarian capsule.
- Perfectly suitable for vegetarians and vegans
Digest-ProGD HP is a patented, high-potency enzyme blend for complete carbohydrate digestion. It contains fungal proteases derived from Aspergillus oryzae, bacterial proteases derived from Bacillus subtilis, plus comprehensive support for carbohydrate digestion with papain, bromelain, and fungal digestive enzymes. Aspergillus oryzae extracts are rich in prolyl endopeptidases and dipeptidyl peptidase IV (DPP-IV) – a multifunctional serine protease that targets proline-containing peptides, such as those found in gliadin and casein, two proteolysis-resistant proteins.
Indeed, the protease activity of Aspergillus oryzae targets the proline-rich 33-mer of gliadin, perhaps the most immunotoxic peptide derived from gliadin. The proline-rich antigenic and immunomodulatory proteins found in gluten are thought to trigger an inflammatory response in patients with celiac disease or gluten sensitivity, often due to accidental exposure to gluten, even in people following a gluten-free diet. Aspergillus oryzae protease supplementation has also been associated with a bifidogenic effect in animals, suggesting a potential probiotic effect, as well as an increase in gut-protective amino acids.
In addition to fungal and bacterial proteases, Digest-ProGD HP provides alpha-amylase, cellulose and hemicellulose for comprehensive support of carbohydrate digestion.