EstroVantage EM™

- Offers a full range of protective compounds from cruciferous vegetables, including I3C, DIM and sulforaphane.
- Provides a unique blend of herbs that improve estrogen metabolism, moving away from carcinogenic metabolites.
- Promotes detoxification of a variety of environmental toxins as well as naturally produced hormones by enhancing phase 1 and phase 2 liver enzymes.
- Contains plants with powerful anti-inflammatory activity.
- Suitable for vegetarians/vegans
EstroVantage EM provides a comprehensive formula of plant-derived compounds that improve the metabolism of estrogens and their metabolites. Cruciferous vegetables contain a variety of glucosinolates, which some studies have linked to a reduction in cancer incidence when consumed in larger quantities, most likely by causing a shift in metabolism toward less carcinogenic estrogen metabolites. EstroVantage EM contains indole-3-carbinol (I3C) and its metabolite 3,3'-diindolylmethane (DIM), as well as sulforaphane from broccoli powder, all of which have been associated with lower rates of neoplastic changes and a more favorable estrogenic profile. Not only do these glucosinolates improve estrogen metabolism, they also reduce inflammation by targeting key signaling molecules, such as Nrf2 and NF-κB.
EstroVantage EM also contains other powerful plant compounds that reduce inflammation and block carcinogenic pathways. Silymarin, an extract of milk thistle, decreases the regulation of genetic products involved in the proliferation of tumor cells, as well as their invasion, angiogenesis and metastasis. This unique combination contains green tea polyphenols, lycopene (tomato extract), turmeric and rosemary extracts, as well as calcium D-glucarate, which has been shown to favorably modify estrogen metabolism and reduce carcinogenic risk. Just recently, a randomized, double-blind, placebo-controlled crossover study demonstrated that taking this formula resulted in significantly higher urinary levels of the protective estrogen metabolite 2-OHE1 and lower levels of the more dangerous estrogen metabolite 16α-OHE1 in premenopausal women. More recently, a randomized, double-blind, placebo-controlled crossover study demonstrated that taking this formula resulted in significantly higher urinary levels of the protective estrogen metabolite 2-OHE1 and lower levels of the more dangerous estrogen metabolite 16α-OHE1 in premenopausal women.