Cycle Matrix (Fertility Matrix) Ovulatory & Oocyte Support

- A powdered blend of evidence-based nutrients for optimal hormonal regulation, egg development and fertility support in women. Peach and mango flavor for improved compliance Designed to support female fertility, including ovulation, oocyte quality, embryonic development and successful gestation. Inositol and NAC support insulin and hormonal balance in polycystic ovary syndrome (PCOS), a condition known to predispose to infertility. Coenzyme Q10 and PQQ provide mitochondrial support to improve egg quality, embryo implantation and embryonic growth. L-arginine increases blood flow to the pelvic organs and promotes endometrial thickness, endometrial receptivity and follicular growth. Folate is provided in the active form of 5-MTHF to improve oocyte development, embryo quality and live birth rate, as well as choline to support the development of the fetal nervous system. Vitex agnus-castus contains diterpene compounds and flavonoids that exert dopaminergic action, reduce prolactin levels and increase endogenous progesterone. Each 276-gram bottle contains a 30-day supply in a peach and mango flavored powder for better compliance and ease of use. Vegan and free of GMOs, gluten, soy and dairy.
Infertility is a growing health problem for Canadians, with up to 1 in 6 couples currently experiencing difficulty conceiving. Of course, infertility can occur as a result of male or female health problems, or a combination of problems with both partners. Although there can be several underlying causes or complicating factors, in women the cause is often related to egg production, egg quality, menstrual irregularities, or hormonal imbalances. Cycle Matrix - Ovulatory & Oocyte Support - from Cyto-Matrix combines a selection of natural health ingredients to target and improve these parameters in women suffering from infertility.
A clinical picture that often leads to infertility in women is polycystic ovary syndrome (PCOS). Physiologically, women with PCOS exhibit insulin resistance and subsequent elevations in androgens and suboptimal progesterone during the luteal phase of the menstrual cycle. This often results in irregular periods, lack of egg maturation, anovulation and infertility. Fortunately, dietary modifications, lifestyle changes, and a number of nutritional supplements have been shown to improve this dysfunctional pattern. Inositol is a great example of a well-studied nutrient to benefit PCOS.
Inositol is a natural isomer of glucose and an important nutrient in the B vitamin family. It is a key component of the cell membrane and increases the sensitivity of cellular receptors to serotonin, acetylcholine, norepinephrine, thyroid hormones and insulin. At doses of 1-4 grams/day, inositol has been shown to improve insulin and glucose control, regulate ovulation, improve egg quality, reduce androgens, and improve fertility in women with PCOS. When combined with folic acid, inositol has been shown to improve in vitro fertilization (IVF) rates. Additionally, one study found that this same combination of nutrients was more effective at inducing ovulation and achieving pregnancy in infertile women with PCOS when directly compared to metformin.
When it comes to folate, although it is classically known for its importance during the first trimester of pregnancy in preventing neural tube defects like spina bifida and anencephaly, research has shown that it also plays a crucial role in fertility and pregnancy preparation. For example, studies have shown that higher folate levels are associated with improved oocyte development, embryo quality and implantation, clinical pregnancies, and live birth rates. Additionally, research has shown that lower folate levels may be accompanied by a higher risk of early miscarriage. The high prevalence of genetic changes in the 5-MTHFR gene strongly suggests that 5-methyltetrahydrofolate (5-MTHF), as opposed to synthetic folic acid, is the necessary form of supplementation in all women to ensure proper absorption and utilization.
N-acetylcysteine ​​(NAC) is another promising treatment for PCOS and infertility. NAC is the rate-limiting substrate necessary for the production of endogenous glutathione, one of the most powerful antioxidant and detoxifying compounds in our body. NAC has been widely used in clinical trials to support optimal health, particularly in liver protection and respiratory disorders. In the context of women's health, NAC has been shown to improve insulin sensitivity, restore ovulation, and improve egg quality in PCOS, while significantly increasing the live birth rate in women with unexplained recurrent pregnancy loss. Finally, NAC has been shown to improve pregnancy rates when used as an adjunct to clomiphene citrate in intrauterine insemination (IUI) cycles in women with unexplained infertility. Mitochondrial dysfunction, resulting from a number of environmental toxins, disease states, or aging, is another identified mechanism behind female infertility. This may explain why coenzyme Q10 (CoQ10), a nutrient known to support mitochondrial function and increase ATP energy production, has shown so much promise in various cases of female infertility. Although CoQ10 has been classically used as a cardiovascular nutrient, recent research has shown that CoQ10 improves conception rates by promoting egg quality, embryo implantation, and embryonic growth. Pyrroloquinoline quinone (PQQ) is a unique antioxidant that has synergistic beneficial effects on mitochondrial function when used with CoQ10.
In some cases of infertility, the health of the endometrial lining may be a contributing concern and L-arginine may be helpful. Larginine has been supplemented primarily for its ability to upregulate nitric oxide and improve blood flow, explaining its benefits on intermittent claudication and physical performance, but it has also been shown to benefit women's health. Increased nitric oxide promotes blood flow to the pelvic organs, supporting endometrial receptivity, endometrial thickness, and follicular growth. One particular study found that L-arginine improved endometrial thickness and pregnancy rates in women with thin endometrial linings.
Finally, some cases of infertility may be linked to low progesterone levels, independent of PCOS. Vitex agnus-castus, commonly known as Chastetree, has long been used to increase progesterone levels and address women's health concerns. The diterpene compounds and flavonoids present in vitex have been shown to exhibit dopaminergic action, thereby reducing prolactin levels and increasing endogenous progesterone. Collectively, these actions would explain why clinical research has shown that vitex can improve menstrual cycle regularity and PMS symptoms. In theory, better hormonal balance can have positive effects on female infertility.
Cycle Matrix - Ovulatory and Oocyte Support combines all of these evidence-based nutrients to support women's fertility, including ovulation, oocyte quality, embryonic development and successful gestation. Additionally, additional choline to positively influence the formation of the fetal brain and spinal cord. Fertility Matrix - Ovulatory and Oocyte Support comes in a convenient peach and mango flavored powder for improved compliance and ease of use. Each 276 gram bottle contains a 30 day supply. Fertility Matrix - Ovulatory and Oocyte Support is vegan and free of GMOs, gluten, soy and dairy.