- 2 billion CFU per capsule of the sporulating bacteria Bacillus coagulans IS-2
- Spore-forming bacteria such as Bacillus coagulans IS-2 are highly resistant to harsh environments of the digestive tract and also demonstrate favorable antimicrobial actions and promote healthy digestion
- Bacillus coagulans IS-2 has been shown to successfully treat IBS in children and adults, constipation, functional abdominal pain in children, and bacterial vaginosis in women receiving adjunctive antibiotic therapy
The relationship between bacteria, digestive function, and overall health is complex, to say the least. Although the past decades of probiotic research have opened many new avenues for medical treatment, many questions remain regarding strain-specific properties and capabilities. Perhaps a problem with traditional probiotic species such as Lactobacillus acidophilus is poor survival through the difficult digestive system. Some species have a survival rate as low as 1-15% throughout the gastrointestinal tract. For this reason, some researchers have focused on sporulating probiotic bacteria such as Bacillus coagulans.
Bacillus coagulans and other spore-forming probiotics naturally enter a protective phase of dormant spores during their life cycle if their survival is threatened. In this spore form, the survival rate is greatly improved because it is extremely resistant to the harsh acidic environment of the stomach, temperature changes, and other potential dangers. Spores of bacillus strains can survive for years in their dormant state, but if given the appropriate stimulus, such as nutrient availability, they can quickly germinate. The appropriate setting for germination and activation appears to be in the small intestine where sugars, amino acids, and purines are widely available.
Of course, it's not enough to have a probiotic that survives. Once germinated and activated, the beneficial effects on the health of the digestive tract and the entire body are even greater. Bacillus coagulans can promote digestion, increase nutrient absorption, and reduce inflammation by producing a variety of enzymes and short-chain fatty acids. Additionally, Bacillus coagulans provides a natural antimicrobial effect by competing for resources and preventing the growth of pathogenic bacteria. It does this by creating an anaerobic, acidic environment in the intestines, making it inhospitable to various pathogens and providing ideal conditions for the proliferation of beneficial bacteria, such as lactobacilli and bifidobacteria species. Some research has even shown that Bacillus coagulans species can secrete bacteriocin, a well-known antibacterial compound, and that they can prevent dysbiosis and related diseases associated with antibiotic use.
Overall, Bacillus coagulans helps promote favorable intestinal flora by improving the diversity, composition and metabolic function of the microbiota. Clinical studies have shown that Bacillus coagulans IS-2 strain is effective in the treatment of irritable bowel syndrome (IBS) in children and adults, constipation, functional abdominal pain in children, and bacterial vaginosis in women receiving adjunctive antibiotic therapy.
Flora-Matrix IBS provides 2 billion CFU per capsule of the resilient sporulating bacteria strain, Bacillus coagulans IS-2. Flora-Matrix IBS is designed to support bowel regularity, manage symptoms of irritable bowel syndrome, promote favorable gut flora, and promote favorable vaginal flora in women. Available in blister packs containing 60 vegetable capsules per box. Flora-Matrix IBS is shelf stable and free of gluten, soy and dairy.
Flora-Matrix IBS belongs to the Flora-Matrix family of probiotics, each containing specialized strains for targeted results. Each Flora-Matrix probiotic contains unique strains with distinct activity and health benefits. These strains are individually selected and well-studied at validated dosages, ensuring targeted clinical outcomes without the need for excessive colony-forming units.
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