I3C SAP

- Targeted nutraceutical therapy
Indole-3-carbinol (I3C) is a phytochemical derived in high concentrations from the Brassica family of vegetables, including broccoli, cauliflower, Brussels sprouts, and cabbage.
I3C and its derivatives have been shown to exert immunomodulatory effects on the human body.
I3C has been shown to exhibit direct antiestrogenic activity via competitive inhibition of estrogen receptors, upregulate cytochrome P450 isoenzymes CYP1A1, CYP1A2 and CYP1B1, thereby increasing estrogen metabolism and shifting estrogen metabolism from the more proliferative (16-OHE1) to the more proliferative species. protective estrogens (2-OHE1).