L-5-MTHF

- Methylated folate, in the form of an entirely natural 6s isomer.
L-5-MTHF provides folate in a bioidentical and bioactive form, 5-methyltetrahydrofolate. L-5-MTHF (the “L” meaning it is the all-natural [6S] isomer) is the active circulating form of folate found in the body and one of many forms found in foods. In nature it is only found in the form of this [6S] isomer; this is why DFH provides 5-MTHF in this natural form rather than in mixed (or racemic) form. L-5-MTHF was designed for patients who have demonstrated an increased need for folate, such as those with A1298C or C677T MTHFR mutations.
Our L-5-MTHF uses the patented Quatrefolic® folate derivative. This innovative form of folate has demonstrated high bioavailability and solubility as well as long-term stability. Quatrefolic L-5-MTHF helps increase blood folate levels significantly better than folic acid.