- CoQ10 plays a beneficial role in the treatment of various chronic disorders characterized by impaired mitochondrial bioenergetics and/or increased oxidative stress, such as heart failure, Parkinson's disease and migraine.
- R-alpha-lipoic acid may have greater bioavailability than the synthetic blend.
- In vivo studies have shown that combinations of CLA and R-alpha-lipoic acid act synergistically to prevent mitochondrial degradation.
- Standardized Ginkgo biloba extract promotes cognitive functioning, neuropsychiatric symptoms and functional abilities in people with vascular dementia and Alzheimer's dementia.
- Resveratrol, a powerful antioxidant present in Japanese knotweed, improves mitochondrial respiration of muscles in obese people, as well as several cardiometabolic risk factors.
- Clinical trials indicate that administration of grape seed proanthocyanidins stimulates mitochondrial function in the skeletal muscle of obese Zucker rats and improves cognitive function in older adults.
- Suitable for vegetarians/vegans
Oxidative damage to mitochondria is a major factor in cellular aging, as well as neurological decline. While lifestyle interventions, such as calorie restriction, help improve mitochondrial function in non-obese young adults, certain supplements such as L-carnitine are also therapeutically beneficial. The salt of L-carnitine, called acetyl-L-carnitine (ALC), is the preferred form in cases of disease and aging because it is better absorbed and easily crosses the blood-brain barrier. CLA has not only been shown to improve mood, but also has an important function in disorders of aging, including fatigue, hypertension, insulin resistance, diabetic neuropathy, and dementia.
Mito AMP also contains Ginkgo biloba extract, resveratrol, R-alpha-lipoic acid, and grape seed proanthocyanidins, all of which modulate mitochondrial function, improve cognitive function, and/or reduce inflammation associated with cognitive decline. Pyrroloquinoline quinone (PQQ) plays a key role in mitochondrial biogenesis through cell signaling (PGC-1 alpha). Clinical trials have shown improved cerebral blood flow and brain function, improved memory when combined with CoQ10, as well as increased vigor and a significant reduction in symptoms of fatigue, tension, low mood and confusion.
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