- 600 mg of N-acetyl-LCysteine per capsule with added glycine and selenium to upregulate endogenous glutathione production and detoxification systems
- Selenium is provided in a glycinate chelate for optimal absorption
- Indicated for exposure to environmental toxins, bronchitis and respiratory disease, acne vulgaris, polycystic ovary syndrome (PCOS), and health problems related to oxidative stress
Environmental toxins have become omnipresent in our daily lives. Although we may not realize the immediate harmful effects of these compounds, they constantly tax our body's detoxification systems and interfere with the ability to perform normal physiological functions. In susceptible individuals, this ongoing strain can lead to glutathione depletion and ultimately contribute to disease development.
Glutathione is one of the most powerful detoxifying compounds in our body and glutathione deficiencies have been linked to chronic diseases such as Parkinson's disease, Alzheimer's disease and even acute cardiovascular events. With this in mind, it is important to ensure that ample stores of glutathione are available to the body during times of stress. N-Acetyl-LCysteine (NAC) supplementation is one of the best known and most researched methods for increasing endogenous production and replenishing glutathione storage levels.
NAC is the rate-limiting substrate needed to make glutathione and has been widely used in clinical trials to support optimal health. For example, NAC is classically used to protect the liver in cases of acetaminophen toxicity and is a well-documented and effective mucolytic agent in bronchitis and other respiratory conditions. NAC has been shown to protect blood vessels, improve acne vulgaris, balance hormones in cases of polycystic ovary syndrome (PCOS) or unexplained infertility, and help detoxify heavy metals. Collectively, NAC is a potent anti-inflammatory and antioxidant agent that can be used in a wide variety of disease states.
Other nutrients are needed to synthesize glutathione and support the body's detoxification systems. Glycine, like cysteine, is an amino acid used as a substrate to make glutathione. Glycine has been studied in isolation and in combination with NAC and shown to be effective in upregulating glutathione production. Selenium, on the other hand, is a mineral that does not act as a substrate for glutathione but rather helps increase glutathione through the upregulation of the enzyme glutathione peroxidase.
NAC-Matrix from Cyto-Matrix provides 600 mg of N-acetyl-L-cysteine, 70 mg of glycine, and 20 mcg of elemental selenium in a glycinate chelate for optimal absorption.
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