Vitamin D3 & K2 · 1000 IU D3 · 120 mcg K2

- Provides clinically effective doses of vitamins D and K per capsule
- Vitamin D3 is most powerful for increasing serum and storage vitamin D levels.
- Uses the optimal form of vitamin K, vitamin K2 menaquinone-7 (MK-7)
- MK-7 has the longest half-life and best extrahepatic distribution of all forms
- A combination of D3 and MK-7 has a synergistic advantage over single nutrient therapy
Vitamin D and vitamin K have diverse and complementary physiological functions, strong associations with chronic and age-related diseases, and a strong body of clinical evidence documenting widespread deficiency and therapeutic potential. Vitamin D has both hormonal and non-hormonal functions, with vitamin D receptors translating into a myriad of physiological actions, from bone metabolism to modulation of immune activity.
Vitamin D regulates the expression of hundreds of genes, influences cell proliferation and signaling, insulin production and sensitivity, and is a critical inhibitor of several inflammatory pathways. Insufficiency has been associated with increased cardiovascular disease, cancer risk, diabetes and metabolic disorders. syndrome, as well as overall mortality.
Vitamin K-dependent proteins (VKDs) are also found almost everywhere and regulate a variety of functions, including cell growth, arterial calcification, and bone metabolism.12 Clinically, low intakes are associated with increased risk of cardiovascular disease, diabetes, cancer, fractures, and all kinds of diseases. cause mortality. Vitamins K and D have complementary physiological functions, and clinical trials have shown synergistic benefits for osteoporosis and cardiovascular disease when used together.